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Grants for Small businesses - Federal

Explore 1,962 grant opportunities

Engineering (ENG): Electrical, Communications, and Computing Systems (ECCS)
$110,000,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Aug 18, 2026

This funding opportunity supports innovative engineering research in electrical, communications, and computing systems, aimed at advancing next-generation technologies and fostering multidisciplinary collaboration among researchers and institutions.

Science and Technology
City or township governments
FY25 Long Range Broad Agency Announcement (BAA) for Navy and Marine Corps Science and Technology
Contact for amount
U.S. Department of Defense (Office of Naval Research)
Federal

Application Deadline

Sep 30, 2026

Date Added

May 30, 2025

This funding opportunity supports innovative research and technology development projects from universities, industry, and research institutions worldwide to enhance the operational capabilities of the Navy and Marine Corps.

Science and Technology
Public and State controlled institutions of higher education
DoW Rare Cancers Resource and Community Development Award
$1,120,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 18, 2026

Date Added

Jun 18, 2026

This funding opportunity supports the development of collaborative research resources and datasets to improve outcomes for individuals affected by rare cancers, emphasizing community engagement and sustainability.

Science and Technology
Nonprofits
Advanced Technological Education
$7,500,000
National Science Foundation
Federal

Application Deadline

Oct 1, 2026

Date Added

Jun 26, 2024

This program provides funding to two-year colleges and their partners to improve technician education in critical technology fields, focusing on workforce development and broadening participation in STEM for underserved communities.

Science and Technology
Public and State controlled institutions of higher education
Major Research Instrumentation Program
$4,000,000
National Science Foundation
Federal

Application Deadline

Nov 16, 2026

Date Added

Nov 25, 2024

This program provides funding to U.S. educational and research institutions for acquiring or developing advanced scientific instruments that enhance research capabilities and training opportunities, particularly for under-resourced organizations.

Science and Technology
Public and State controlled institutions of higher education
Cyberinfrastructure for Public Access and Open Science (CI PAOS)
$600,000
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Apr 10, 2024

This funding initiative supports collaborative projects that enhance research data infrastructure and promote open science by bringing together researchers, data management professionals, and libraries to improve data accessibility and usability.

Science and Technology
Public and State controlled institutions of higher education
Injury Prevention and Control Research and State and Community Based Programs - RFA-DD-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 13, 2023

This funding opportunity provides financial support for research and community programs focused on preventing injuries, particularly targeting vulnerable populations and public health challenges.

Health
County governments
Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)
$450,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 10, 2026

Date Added

Sep 9, 2025

This funding opportunity supports innovative research projects that develop new technologies for cancer detection and treatment, targeting a wide range of eligible organizations including universities, nonprofits, and small businesses.

Health
Public and State controlled institutions of higher education
DoW Amyotrophic Lateral Sclerosis Research Program, Clinical Outcomes and Biomarkers Award
$1,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 30, 2026

Date Added

May 5, 2026

This funding opportunity supports researchers developing and validating clinical outcomes and biomarkers to improve ALS clinical trials, with a strong emphasis on community collaboration and engagement from individuals affected by the disease.

Health
Nonprofits
Advanced Research Announcement (ARA) FA9300-25-S-6001
$500,000,000
U.S. Department of Defense (Air Force Research Laboratory, Aerospace Systems Directorate)
Federal

Application Deadline

Sep 25, 2035

Date Added

Oct 6, 2025

This grant invites U.S. organizations, particularly small businesses, to propose innovative research and technology demonstrations that enhance rocket propulsion, missile systems, and digital engineering for national defense.

Science and Technology
For profit organizations other than small businesses
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
$350,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 15, 2027

Date Added

Sep 19, 2024

This funding opportunity supports researchers and institutions in developing innovative, non-addictive pain treatments through early-stage drug discovery and assay development, with a focus on alternatives to opioid therapies.

Education
State governments
FY 2024 2026 Broad Agency Announcement (BAA), Office of Oceanic and Atmospheric Research (OAR)
Contact for amount
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Sep 30, 2026

Date Added

Oct 10, 2024

The "FY 2024 – 2026 Broad Agency Announcement (BAA), Office of Oceanic and Atmospheric Research (OAR)" grant is a funding opportunity by NOAA for educational institutions, nonprofits, and commercial organizations to support research, innovative projects, and educational outreach in areas like ocean exploration, climate adaptation, weather readiness, and coastal community resilience, with a focus on interdisciplinary projects that align with NOAA's mission and strategic goals.

Business and Commerce
Public and State controlled institutions of higher education
Rural Energy for America Program (REAP) : Renewable Energy Systems Grant
$1,000,000
U.S. Department of Agriculture (Rural Development)
Federal
Rolling

Application Deadline

Not specified

Date Added

Feb 1, 2024

This program provides financial assistance to farmers and small rural businesses for implementing renewable energy projects and improving energy efficiency.

Energy
Small businesses
DOD Defense Health Agency (DHA) Research Development FY23-FY27 BROAD AGENCY ANNOUNCEMENT for Extramural Medical Research
Contact for amount
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Sep 30, 2027

Date Added

Sep 22, 2022

This funding opportunity supports innovative medical research projects that enhance the health and readiness of U.S. service members and benefit civilian populations, inviting submissions from a wide range of qualified applicants.

Science and Technology
Nonprofits
INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 15, 2028

Date Added

Sep 26, 2025

This funding opportunity provides financial support for innovative research projects aimed at improving the health and quality of life for individuals with Down syndrome, targeting a diverse range of applicants including educational institutions, nonprofits, and for-profit organizations.

Health
Public and State controlled institutions of higher education
LPS Qubit Collaboratory (LQC)
$2,400,000
U.S. Department of Defense (Dept of the Army -- Materiel Command)
Federal

Application Deadline

Apr 30, 2027

Date Added

Apr 16, 2021

This funding opportunity supports researchers and institutions working on innovative quantum information science and technology projects, particularly in qubit development, to advance fundamental discoveries and build a skilled workforce in the field.

Science and Technology
Nonprofits
Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 9, 2027

Date Added

Jun 3, 2025

This funding opportunity supports educational programs that enhance training in innovative research methods for behavioral and social sciences, targeting a wide range of organizations including universities and nonprofits.

Education
State governments
Advanced Nuclear Energy Licensing Cost-Share Grant Program
$8,000,000
U.S. Department of Energy (Idaho Field Office)
Federal

Application Deadline

Sep 30, 2026

Date Added

Jan 9, 2025

This program provides financial support to U.S.-based organizations for activities that help reduce the costs associated with licensing advanced nuclear reactors, promoting innovation and commercialization in clean energy technologies.

Energy
State governments
Engineering Design and Systems Engineering (EDSE)
Contact for amount
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Jan 6, 2025

This grant supports researchers in advancing design and systems engineering by funding innovative projects that improve the creation and functionality of engineered artifacts across various disciplines.

Science and Technology
City or township governments
NCI Community Oncology Research Program (NCORP) Community Sites (UG1 Clinical Trial Not Allowed)
$73,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 18, 2026

Date Added

May 22, 2026

This funding opportunity provides financial support to community healthcare organizations in the U.S. to enhance their capacity for participating in cancer research and improving cancer care delivery for diverse populations.

Health
Nonprofits