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Grants for Small businesses - Federal

Explore 1,962 grant opportunities

Mind, Machine and Motor Nexus (M3X)
Contact for amount
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Apr 17, 2025

This grant supports researchers developing intelligent systems that interact with humans in safe and effective ways, particularly in complex environments like elder care and disaster response.

Science and Technology
City or township governments
Advancing Healthcare for Older Adults from Populations that Experience Health Disparities (R01 - Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2028

Date Added

Aug 28, 2024

This funding opportunity supports research projects aimed at improving healthcare for older adults from underserved populations, focusing on reducing health disparities and enhancing patient-centered care.

Education
State governments
Evaluations of Practices for Program Integrity and Fraud Prevention
$425,000
U.S. Department of Health and Human Services (Administration for Children and Families)
Federal

Application Deadline

Sep 8, 2026

Date Added

May 18, 2026

This funding opportunity provides financial support to Child Care and Development Fund Lead Agencies and their research partners to evaluate and improve strategies for preventing fraud and ensuring program integrity in child care services.

Income Security and Social Services
State governments
DoW Melanoma Research Program Melanoma Academy Scholar Award
$770,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 14, 2026

Date Added

May 6, 2026

This funding opportunity supports early-career researchers focused on innovative melanoma research to improve prevention, detection, and survivorship outcomes for military personnel and the general public.

Health
Nonprofits
DoW Melanoma Research Program Idea Award
$560,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 14, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative and high-risk research projects aimed at advancing the understanding and treatment of melanoma, targeting both military and civilian populations.

Health
Nonprofits
DoW Melanoma Research Program Survivorship Research Award
$1,020,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 14, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at improving the health and well-being of melanoma survivors and their families, focusing on quality of life and long-term care strategies.

Health
Nonprofits
Needipedia - Commercial Solutions Opening - Cso
Contact for amount
Defense Intelligence Agency (DIA)
Federal

Application Deadline

Dec 26, 2028

Date Added

Mar 20, 2025

This opportunity invites a wide range of participants, including businesses, consultants, and academic institutions, to propose innovative solutions that enhance the operational efficiency and technological capabilities of the Department of Defense.

Science and Technology
For profit organizations other than small businesses
Autism Centers of Excellence R01
$10,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 2, 2026

Date Added

Sep 24, 2025

This funding opportunity supports collaborative research projects focused on advancing the understanding of autism spectrum disorders through multi-site partnerships among various research institutions and organizations.

Health
Public and State controlled institutions of higher education
Stimulating Hematology Investigation: New Endeavors (SHINE) (R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 6, 2028

Date Added

Nov 7, 2024

This grant provides funding for innovative research on non-malignant blood disorders, focusing on understanding and improving treatments for conditions related to hematology, and is open to universities, nonprofits, and government entities.

Food and Nutrition
Nonprofits
Injury Prevention and Control Research and State and Community Based Programs - RFA-OE-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 20, 2023

This funding opportunity provides financial support to state and community organizations, universities, and nonprofits for research and programs focused on preventing and controlling injuries.

Health
State governments
INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)
$500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 15, 2028

Date Added

Sep 26, 2025

This funding opportunity supports innovative research projects aimed at improving health outcomes and quality of life for individuals with Down syndrome, inviting a diverse range of applicants from various sectors to propose groundbreaking ideas.

Health
Private institutions of higher education
Advancing Global Health
$250,000,000
U.S. Department of State (Bureau of Global Health Security and Diplomacy)
Federal

Application Deadline

Sep 15, 2026

Date Added

Aug 4, 2026

This grant provides funding to organizations that implement health initiatives in partnership with foreign governments, aiming to improve global health outcomes and strengthen health systems.

Health
Nonprofits
ROSES25: A.14 Atmosphere
$8,000,000
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Oct 20, 2026

Date Added

Jul 21, 2026

This funding opportunity supports U.S. organizations, including universities and nonprofits, in conducting research on atmospheric processes using NASA's airborne campaign data to improve understanding of air quality, weather systems, and climate interactions.

Science and Technology
Nonprofits
Facility and Instrumentation Request Process
$75,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

May 21, 2025

This grant provides funding for researchers and educational institutions to access advanced atmospheric science facilities and instruments, enabling high-level observational research and educational initiatives.

Science and Technology
Nonprofits
EnsuringPro-American WorkerCritical MineralsSupply Chain inthe Western Hemisphere
$5,000,000
U.S. Department of Labor (Bureau of International Labor Affairs)
Federal

Application Deadline

Sep 21, 2026

Date Added

Jul 17, 2026

This funding opportunity provides financial support to U.S. and eligible international organizations to improve labor standards and transparency in critical mineral supply chains in Chile and Argentina, ultimately benefiting American workers and manufacturers.

Employment Labor and Training
Nonprofits
DoW Alzheimers Transforming Diagnosis Award
$1,700,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 24, 2026

Date Added

May 4, 2026

This funding opportunity supports innovative research projects aimed at improving the diagnosis and monitoring of Alzheimer's disease and related dementias, particularly focusing on military health relevance and addressing health disparities in diverse populations.

Health
Nonprofits
DoW Breast Cancer, Breakthrough Award Levels 1 and 2
$3,350,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 18, 2026

Date Added

May 5, 2026

This funding opportunity supports innovative research aimed at making significant breakthroughs in breast cancer prevention, diagnosis, and treatment, specifically benefiting Service Members, Veterans, their Families, and the general public.

Health
Nonprofits
ROSES25: A.13 Accelerating Earth Solutions
$1,200,000
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Oct 15, 2026

Date Added

Jul 20, 2026

This funding opportunity provides financial support to U.S.-based organizations for projects that utilize Earth observing satellite data to improve decision-making in areas like agriculture, disaster resilience, and public health.

Science and Technology
Nonprofits
Proactive Health Solutions Grant
Contact for amount
US Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 5, 2029

Date Added

Jun 19, 2025

This funding opportunity is designed to support innovative organizations and researchers in developing proactive health solutions that prevent disease and promote wellness across the United States.

Health
For profit organizations other than small businesses
Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)
$275,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 17, 2028

Date Added

May 29, 2025

This funding opportunity supports innovative research aimed at developing new therapies for challenging diseases by targeting previously considered undruggable biological elements, such as disordered proteins and metabolites.

Health
Public and State controlled institutions of higher education