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Grants for Small businesses - Federal

Explore 1,962 grant opportunities

Digital Health Technology Derived Biomarkers and Outcome Assessments for Remote Monitoring and Endpoint Development (UG3/UH3 - Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2027

Date Added

Nov 14, 2024

This funding opportunity supports the development of digital health tools to improve remote monitoring and clinical trial outcomes across multiple diseases, targeting researchers and organizations with expertise in health technology and patient engagement.

Education
State governments
Injury Prevention and Control Research and State and Community Based Programs - RFA-TS-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 19, 2023

This funding opportunity provides financial support for a variety of organizations, including state agencies, academic institutions, and nonprofits, to develop and implement programs aimed at preventing injuries and improving public health.

Health
State governments
Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)
$350,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 2, 2027

Date Added

Nov 1, 2024

This funding opportunity supports research institutions and organizations in developing personalized probiotic therapies by investigating how individual biological differences affect probiotic responses.

Education
State governments
Algebra and Number Theory
Contact for amount
National Science Foundation
Federal

Application Deadline

Oct 9, 2026

Date Added

Oct 28, 2024

This funding opportunity supports researchers in mathematics, particularly in areas like algebra and number theory, to advance fundamental knowledge and foster collaboration through individual projects, conferences, and workshops.

Science and Technology
Nonprofits
Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21)
$365,000
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Dec 8, 2026

Date Added

Oct 16, 2025

This funding opportunity provides financial support for innovative research projects aimed at improving the health and well-being of individuals affected by the September 11 attacks, targeting a wide range of eligible organizations, including universities, nonprofits, and government entities.

Health
City or township governments
Autism Centers of Excellence P50
$10,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 2, 2026

Date Added

Sep 24, 2025

This funding opportunity supports innovative research projects aimed at advancing the understanding of autism spectrum disorder, inviting diverse organizations and researchers to collaborate on interdisciplinary studies.

Health
State governments
Rfa-Ck-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides financial support for a wide range of organizations, including states, universities, and nonprofits, to enhance or expand existing injury prevention and control research projects.

Health
State governments
BRAIN Initiative: Research Resource Grants for Technology Integration and Dissemination (U24 Clinical Trial Not Allowed)
$10,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 6, 2028

Date Added

Feb 10, 2026

This funding opportunity supports the dissemination and integration of validated neuroscience tools and resources to enhance research and understanding of brain function and disorders, targeting a wide range of eligible applicants including educational institutions, nonprofits, and businesses.

Science and Technology
State governments
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2028

Date Added

Dec 19, 2024

This funding opportunity supports a wide range of research projects aimed at advancing medical knowledge and improving health, available to various organizations including universities, nonprofits, and businesses.

Health
Nonprofits
FY2026 Implementation of the Quagga and Zebra Mussel Action Plan (QZAP) in the Western United States
$600,000
U.S. Department of the Interior (Fish and Wildlife Service)
Federal

Application Deadline

Oct 24, 2026

Date Added

Aug 26, 2026

This funding opportunity provides financial support for projects aimed at preventing the spread of invasive quagga and zebra mussels in Western U.S. waters, targeting organizations and entities involved in conservation, research, and public outreach.

Environment
State governments
Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)
$275,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 3, 2027

Date Added

Dec 6, 2024

This funding opportunity supports innovative research projects that utilize existing datasets to investigate substance use behaviors and related disorders, with a particular focus on HIV, aiming to enhance prevention and treatment strategies.

Health
Public and State controlled institutions of higher education
Professional Formation of Engineers
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 20, 2026

This funding opportunity supports projects that enhance the education and professional development of engineers throughout their careers, aiming to strengthen the engineering workforce in the United States.

Science and Technology
Nonprofits
Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
$750,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2028

Date Added

Nov 1, 2024

This funding opportunity supports pilot projects that evaluate new mental health interventions aimed at improving long-term outcomes for individuals recovering from acute mental health conditions.

Health
State governments
Rfa-Eh-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides financial support to states, counties, universities, small businesses, and nonprofit organizations for initiatives focused on injury prevention and community health improvement across the nation.

Health
State governments
NCMRR Early Career Research Award (R03 Clinical Trial Optional)
$200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 16, 2027

Date Added

Nov 19, 2024

This funding opportunity supports early-career researchers in rehabilitation sciences to develop independent projects that advance understanding and treatment of disabilities, with a focus on incorporating the perspectives of individuals with lived experiences.

Education
Public and State controlled institutions of higher education
Annual Recurring University Training and Research
$750,000
U.S. Department of Energy (National Energy Technology Laboratory)
Federal

Application Deadline

Oct 16, 2026

Date Added

Aug 17, 2026

This funding opportunity provides financial support to U.S. colleges and universities for innovative research and training in subsurface energy production, aimed at enhancing student involvement and collaboration with industry partners.

Energy
Public and State controlled institutions of higher education
Protecting the American Seafood Supply Chain by Countering Unfair Labor Practices and Illegal, Unreported, and Unregulated (IUU)Fishing
$11,000,000
U.S. Department of Labor (Bureau of International Labor Affairs)
Federal

Application Deadline

Sep 21, 2026

Date Added

Jul 17, 2026

This funding opportunity provides $11 million to organizations working to improve the American seafood supply chain by addressing unfair labor practices and combating illegal fishing activities.

Employment Labor and Training
Nonprofits
DoW Joint Warfighter Medical, Military Medical Research and Development Award
$3,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 16, 2026

Date Added

Jun 18, 2026

This funding opportunity provides financial support for organizations to continue advanced military medical research projects that have previously received Department of Defense funding, focusing on improving healthcare solutions for Service Members and military beneficiaries.

Science and Technology
Nonprofits
Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 2, 2028

Date Added

May 13, 2025

This funding opportunity supports the establishment of Clinical Coordinating Centers for multi-site clinical trials aimed at improving health outcomes and reducing disparities across diverse U.S. populations.

Health
Public and State controlled institutions of higher education
Measurement Science and Engineering (MSE) Research Grant Programs
$12,000,000
U.S. Department of Commerce (National Institute of Standards and Technology)
Federal

Application Deadline

Sep 15, 2026

Date Added

May 15, 2025

This funding opportunity provides financial support for a wide range of research and collaborative projects in measurement science and engineering, targeting universities, nonprofits, and businesses to enhance innovation and competitiveness in various technical fields.

Science and Technology
Nonprofits