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Grants for Small businesses - Federal

Explore 1,853 grant opportunities

INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 15, 2028

Date Added

Sep 26, 2025

This funding opportunity provides financial support for innovative research projects aimed at improving the health and quality of life for individuals with Down syndrome, targeting a diverse range of applicants including educational institutions, nonprofits, and for-profit organizations.

Health
Public and State controlled institutions of higher education
LPS Qubit Collaboratory (LQC)
$2,400,000
U.S. Department of Defense (Dept of the Army -- Materiel Command)
Federal

Application Deadline

Apr 30, 2027

Date Added

Apr 16, 2021

This funding opportunity supports researchers and institutions working on innovative quantum information science and technology projects, particularly in qubit development, to advance fundamental discoveries and build a skilled workforce in the field.

Science and Technology
Nonprofits
Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 9, 2027

Date Added

Jun 3, 2025

This funding opportunity supports educational programs that enhance training in innovative research methods for behavioral and social sciences, targeting a wide range of organizations including universities and nonprofits.

Education
State governments
Advanced Nuclear Energy Licensing Cost-Share Grant Program
$8,000,000
U.S. Department of Energy (Idaho Field Office)
Federal

Application Deadline

Sep 30, 2026

Date Added

Jan 9, 2025

This program provides financial support to U.S.-based organizations for activities that help reduce the costs associated with licensing advanced nuclear reactors, promoting innovation and commercialization in clean energy technologies.

Energy
State governments
Research Experiences and/or Mentoring Networks through Research Education to Enhance Clinician-Scientists' Participation in NIDCDs Research (R25 Clinical Trial Not Allowed)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 29, 2026

Date Added

Apr 3, 2025

This funding opportunity supports educational programs that provide hands-on research experiences and mentoring for clinician-scientists, particularly those from diverse backgrounds, to enhance their involvement in research related to hearing, balance, taste, smell, voice, speech, and language.

Education
State governments
Atmosphere Cluster
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Sep 26, 2024

This grant provides funding for researchers studying atmospheric processes, including weather, climate, and air quality, with a focus on innovative experimental and observational methods.

Science and Technology
Nonprofits
Environmental influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Access (X01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 1, 2028

Date Added

May 15, 2025

This grant provides access to valuable data and biospecimens for researchers studying maternal and child health, requiring them to secure separate funding for their projects.

Health
Public and State controlled institutions of higher education
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U01 Clinical Trial Optional)
Contact for amount
National Institute of Mental Health (NIMH)
Federal

Application Deadline

Oct 25, 2026

Date Added

Apr 18, 2025

This funding opportunity supports partnerships between academic institutions and industry to develop new drugs and devices for treating mental health disorders, encouraging innovative research and early clinical trials.

Health
Public and State controlled institutions of higher education
Forecast to Publish a Funding Opportunity Announcement for Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)
$300,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 19, 2027

Date Added

Jul 3, 2025

This funding opportunity provides financial support for the early-stage development of innovative informatics technologies that enhance cancer research and management, targeting a wide range of eligible organizations including universities, nonprofits, and for-profit entities.

Science and Technology
Public and State controlled institutions of higher education
DoD Lupus, Impact Award
$1,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 19, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at significantly advancing the understanding and treatment of lupus, targeting both established and new researchers in the field.

Science and Technology
Nonprofits
Environmental Engineering
$10,000,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 3, 2025

This program provides funding for researchers to develop innovative engineering solutions that protect human and ecological health by addressing pollution and improving environmental quality.

Environment
Public and State controlled institutions of higher education
2027 Quality Samples Program
$2,500,000
U.S. Department of Agriculture (Foreign Agricultural Service)
Federal

Application Deadline

Aug 14, 2026

Date Added

Jun 11, 2026

This grant provides funding to U.S. organizations involved in exporting agricultural products, enabling them to send samples to foreign buyers to promote and build demand for U.S. commodities.

Agriculture
Nonprofits
Neutron Strategic Technology Advanced Research Announcement
Contact for amount
Air Force Research Laboratory
Federal

Application Deadline

Oct 1, 2026

Date Added

Sep 8, 2025

This funding opportunity is designed to support research and development in nuclear technologies that enhance U.S. national defense capabilities, targeting universities, industry, and research organizations involved in nuclear deterrence and related fields.

Science and Technology
For profit organizations other than small businesses
DoW Peer Reviewed Medical, Technology/Therapeutic Development Award
$5,600,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 6, 2026

Date Added

May 11, 2026

This funding opportunity supports organizations in developing advanced medical technologies and therapeutic products that improve healthcare for military Service Members, Veterans, and their Families.

Science and Technology
Nonprofits
DoW Autism Idea Development Award
$750,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 22, 2026

Date Added

May 22, 2026

This grant provides funding for innovative research projects that aim to improve understanding and outcomes for individuals with autism and their families, supporting independent researchers and interdisciplinary collaborations.

Health
Nonprofits
Human Networks and Data Science
$800,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Feb 14, 2025

This program provides funding for researchers and institutions to develop databases and analytical tools or conduct theory-driven studies that use data and network science to better understand human behavior in social, economic, and behavioral contexts.

Science and Technology
Public and State controlled institutions of higher education
Mechanisms that Impact Cancer Risk after Bariatric Surgery (R21 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2028

Date Added

Sep 6, 2024

This grant provides funding for innovative research exploring how bariatric surgery may influence cancer risk through biological mechanisms, targeting universities, nonprofits, and small businesses engaged in early-stage studies.

Education
State governments
NRL Long Range Broad Agency Announcement (BAA) for Basic and Applied Research
Contact for amount
U.S. Department of Defense (Naval Research Laboratory)
Federal

Application Deadline

Sep 30, 2026

Date Added

Jun 4, 2025

This funding opportunity supports innovative research projects from universities, private companies, and nonprofit institutions that advance scientific and technological capabilities for the U.S. Navy and Marine Corps.

Science and Technology
Public and State controlled institutions of higher education
DoW Spinal Cord Injury, Translational Research Award
$2,160,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 12, 2026

Date Added

May 6, 2026

This funding opportunity supports researchers working on innovative spinal cord injury treatments and interventions that can improve the lives of military personnel, veterans, and their families.

Health
Nonprofits
Catalyze: Product Definition for Small Molecules, Biologics and Combination Products - Target Identification and Validation, and Preliminary Product/Lead Series Identification (R61/R33 Clinical Trials Not Allowed)
$1,200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 21, 2027

Date Added

Nov 25, 2024

This funding opportunity supports researchers and organizations in developing and validating new therapeutic targets and preliminary compounds for diseases related to heart, lung, blood, and sleep disorders, with a focus on early-stage translational research.

Science and Technology
Public and State controlled institutions of higher education