Grants for Small businesses - Federal

This grant provides funding for innovative research and development projects that enhance U.S. space operations and cybersecurity capabilities, targeting a wide range of applicants including private companies, universities, and research organizations.

This funding opportunity provides financial support for invited organizations to conduct assessments and deliver enhanced training aimed at improving the effectiveness and community engagement of law enforcement agencies across the United States.

This program provides funding to rural communities for projects that improve access to education and healthcare through advanced telecommunications technologies.

This funding opportunity supports research and technology development in advanced telecommunications systems for various industries, including healthcare and transportation, targeting academic institutions, nonprofits, and businesses to foster innovation and collaboration.

To implement a project aimed at advancing U.S. foreign policy and national security priorities by supporting initiatives that make decision-making structures and processes in fragile, conflict, or crisis-affected contexts more reflective of and responsive to the needs and perspectives of partner states to ensure strategic trade control systems meet international standards and by engaging on bilateral, regional and multilateral levels with foreign governments to aid in the establishment of independent capabilities to regulate transfers of weapons of mass destruction, WMD-related items, conventional arms, and related dual-use items, and to detect, interdict, investigate, and prosecute illicit transfers of such items.

This funding opportunity provides $2 million to selected nonprofit organizations and small businesses to update and enhance impaired driving training curricula for law enforcement agencies across the U.S.

The EHDA supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in the TSC research field. The studies supported by this award mechanism are expected to generate preliminary data for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on a strong scientific rationale and study design. Applications should demonstrate the ability to achieve interpretable results in the absence of preliminary data supporting the hypothesis.The following are important aspects of the EHDA: Innovation: Innovative research may introduce a new paradigm, challenge existing paradigms, examine existing problems from new perspectives, or exhibit other highly creative qualities. Research that is an incremental advance upon published data is not considered innovative and is not consistent with the intent of the award mechanism. Although not all-inclusive, the following examples are ways in which the proposed research project may be innovative: Explores a novel idea and/or research question in TSC research and/or patient care. Uses or develops novel methods or technologies to address a question in TSC research and/or patient care. Applies or adapts existing methods or technologies for novel TSC research or clinical purposes that differ fundamentally from those originally intended.

This funding opportunity supports a wide range of organizations in developing innovative treatments and testing strategies to prevent and modify epilepsy and other neurological disorders.

This funding opportunity supports researchers aiming to enhance existing breast cancer clinical studies by extending follow-up activities, improving data analysis, and maximizing the use of previously collected patient data and biospecimens.

This grant provides funding for state and community programs, as well as research initiatives, aimed at developing and promoting effective strategies to prevent and control injuries and violence, with a focus on health equity and community conditions.

This funding opportunity is designed to support U.S.-based small businesses in developing innovative quantum computing solutions for complex energy-related challenges in computational chemistry and materials science.

This Notice informs that NIA intends to publish a Notice of Funding Opportunity (NOFO) inviting applications from mid-career investigators for mentored career enhancement awards focused on cross-disciplinary training to broaden and strengthen the investigator's capability to lead future comparative studies of the factors contributing to differences in life spans between human and nonhuman primate species. The NOFO is intended to provide support for experienced investigators with expertise in human and/or nonhuman primate (NHP) studies to do the following: 1) Augment or redirect their research program by acquiring expertise in other fields related to comparative primate research and aging 2) Develop collaborations with research fields with which they do not commonly interact This Notice is being provided to allow potential applicants sufficient time to identify potential mentors and prepare well-developed career enhancement plans. The NOFO is expected to be published in June 2024 with an anticipated application due date in November 2024. These are estimated time frames, and they may change. The NOFO is expected to utilize the K18 Career Enhancement Award activity code. It is expected that the NOFO will not allow clinical trials. Additional details of the planned NOFO are provided below.

This funding opportunity provides financial support to organizations that deliver comprehensive HIV care and essential services for women, infants, children, and youth affected by HIV in designated geographic areas.

This funding opportunity provides financial support to small businesses in the U.S. for conducting exploratory clinical trials or biomarker validation studies aimed at advancing therapies for neurological disorders.

This funding opportunity provides financial support to a variety of organizations working in Kenya to strengthen public health systems and improve responses to infectious disease threats.

This funding opportunity supports collaborative research consortia focused on understanding the brain-body interactions that lead to excessive alcohol use and Alcohol Use Disorder, aiming to identify biological markers for prevention and intervention.

This grant provides funding for innovative technologies that improve the Navy and Marine Corps' electronic warfare and surveillance capabilities, targeting researchers and companies developing advanced signal processing, countermeasures, and ISR systems.

This funding opportunity supports partnerships that include domestic academic institutions to develop innovative technologies for extracting and refining rare earth elements from unconventional sources, enhancing the U.S. supply chain and reducing environmental impact.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for identification of small molecules that function to elucidate the biology of disease as chemical probes or function as agonists or antagonists of disease target(s) for therapy or immunotherapy. The NOFO is intended to support discovery research for the identification of validated hits relevant to health-related outcomes of participating NIH Institutes. Stages of discovery research covered by this NOFO include: 1) assay development for specific biological targets and disease mechanisms relevant to the mission of participating NIH Institutes with the intent to screen for small molecule compounds that show potential as probes for use in advancing knowledge about the known targets, identifying new targets, or as pre-therapeutic leads; 2) screen implementation high throughput target-focused approaches or moderate throughput phenotypic- and fragment-based approaches to identify initial screening hits; 3) hit validation, including implementation of secondary assays that are orthogonal to the primary assay, advanced cheminformatics analysis and initial medicinal chemistry inspection to prioritize the hit set, and follow-up assays to characterize mode and mechanism of action of the validated hits; 4) hit-to-lead optimization, including SAR to optimize target engagement, selectivity and to minimize chemical liabilities, ADME, PK and PD studies, and, if appropriate, in vivo modeling to test efficacy or biological effects.

This funding opportunity provides financial support for researchers to analyze existing data on late talking children, particularly focusing on underrepresented populations, to better understand their developmental trajectories and improve language outcomes.