Grants for Small businesses - Federal
Explore 1,853 grant opportunities
Application Deadline
Aug 14, 2025
Date Added
Sep 29, 2023
This funding opportunity supports research institutions and organizations conducting experimental studies with human participants to explore new brain stimulation techniques for treating substance use disorders.
Application Deadline
Jul 18, 2025
Date Added
Jan 17, 2025
This funding opportunity supports U.S.-based businesses, academic institutions, and non-profits in developing innovative solutions for sustainable supply chains that reduce waste and promote recycling, while also fostering community benefits and workforce development.
Application Deadline
May 14, 2026
Date Added
Mar 20, 2026
This funding opportunity supports research projects aimed at reducing violence against women and girls and improving responses within the criminal justice system, targeting issues such as domestic violence, sexual violence, and stalking.
Application Deadline
Jul 8, 2026
Date Added
Jun 18, 2026
This funding opportunity is designed to support innovative research and development in advanced materials analysis technologies, targeting a wide range of organizations, including academic institutions and private companies, to enhance capabilities for defense applications such as material identification and forensic analysis.
Application Deadline
Jul 14, 2026
Date Added
Jun 5, 2025
This funding opportunity provides financial support for early-stage researchers to conduct small-scale studies that inform public health policies related to tobacco use and regulation.
Application Deadline
Feb 5, 2025
Date Added
Nov 25, 2024
This funding opportunity supports researchers and organizations in developing advanced tissue-engineered technologies that mimic cancer biology to improve cancer detection, treatment, and prevention.
Application Deadline
Jul 17, 2025
Date Added
Feb 28, 2024
This funding opportunity provides financial support for organizations to develop and validate digital therapeutic technologies designed to treat substance use disorders, with the goal of achieving FDA authorization.
Application Deadline
Jan 24, 2025
Date Added
May 22, 2024
This grant provides funding for clinical trials investigating the safety and effectiveness of amyloid-beta antibody therapies in patients with mild cognitive impairment or dementia who also show signs of Lewy Body Dementia, with a focus on diverse and underrepresented populations.
Application Deadline
Aug 27, 2025
Date Added
May 27, 2025
This funding opportunity supports innovative research projects aimed at developing new therapies for Amyotrophic Lateral Sclerosis (ALS), encouraging high-risk ideas that include biomarker development to guide future clinical applications.
Application Deadline
Jun 30, 2026
Date Added
May 4, 2026
This program provides funding to rural communities for projects that improve access to education and healthcare through advanced telecommunications technologies.
Application Deadline
Not specified
Date Added
May 21, 2025
This funding opportunity supports research and technology development in advanced telecommunications systems for various industries, including healthcare and transportation, targeting academic institutions, nonprofits, and businesses to foster innovation and collaboration.
Application Deadline
May 29, 2024
Date Added
Mar 30, 2024
To implement a project aimed at advancing U.S. foreign policy and national security priorities by supporting initiatives that make decision-making structures and processes in fragile, conflict, or crisis-affected contexts more reflective of and responsive to the needs and perspectives of partner states to ensure strategic trade control systems meet international standards and by engaging on bilateral, regional and multilateral levels with foreign governments to aid in the establishment of independent capabilities to regulate transfers of weapons of mass destruction, WMD-related items, conventional arms, and related dual-use items, and to detect, interdict, investigate, and prosecute illicit transfers of such items.
Application Deadline
Aug 1, 2024
Date Added
Apr 22, 2024
The EHDA supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in the TSC research field. The studies supported by this award mechanism are expected to generate preliminary data for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on a strong scientific rationale and study design. Applications should demonstrate the ability to achieve interpretable results in the absence of preliminary data supporting the hypothesis.The following are important aspects of the EHDA: Innovation: Innovative research may introduce a new paradigm, challenge existing paradigms, examine existing problems from new perspectives, or exhibit other highly creative qualities. Research that is an incremental advance upon published data is not considered innovative and is not consistent with the intent of the award mechanism. Although not all-inclusive, the following examples are ways in which the proposed research project may be innovative: Explores a novel idea and/or research question in TSC research and/or patient care. Uses or develops novel methods or technologies to address a question in TSC research and/or patient care. Applies or adapts existing methods or technologies for novel TSC research or clinical purposes that differ fundamentally from those originally intended.
Application Deadline
Feb 20, 2026
Date Added
Sep 24, 2025
This funding opportunity supports a wide range of organizations in developing innovative treatments and testing strategies to prevent and modify epilepsy and other neurological disorders.
Application Deadline
Jul 8, 2026
Date Added
May 5, 2026
This funding opportunity supports researchers aiming to enhance existing breast cancer clinical studies by extending follow-up activities, improving data analysis, and maximizing the use of previously collected patient data and biospecimens.
Application Deadline
Oct 13, 2025
Date Added
Oct 20, 2023
This grant provides funding for state and community programs, as well as research initiatives, aimed at developing and promoting effective strategies to prevent and control injuries and violence, with a focus on health equity and community conditions.
Application Deadline
Feb 6, 2025
Date Added
Dec 30, 2024
This funding opportunity is designed to support U.S.-based small businesses in developing innovative quantum computing solutions for complex energy-related challenges in computational chemistry and materials science.
Application Deadline
Nov 1, 2024
Date Added
Apr 23, 2024
This Notice informs that NIA intends to publish a Notice of Funding Opportunity (NOFO) inviting applications from mid-career investigators for mentored career enhancement awards focused on cross-disciplinary training to broaden and strengthen the investigator's capability to lead future comparative studies of the factors contributing to differences in life spans between human and nonhuman primate species. The NOFO is intended to provide support for experienced investigators with expertise in human and/or nonhuman primate (NHP) studies to do the following: 1) Augment or redirect their research program by acquiring expertise in other fields related to comparative primate research and aging 2) Develop collaborations with research fields with which they do not commonly interact This Notice is being provided to allow potential applicants sufficient time to identify potential mentors and prepare well-developed career enhancement plans. The NOFO is expected to be published in June 2024 with an anticipated application due date in November 2024. These are estimated time frames, and they may change. The NOFO is expected to utilize the K18 Career Enhancement Award activity code. It is expected that the NOFO will not allow clinical trials. Additional details of the planned NOFO are provided below.
Application Deadline
Jul 13, 2026
Date Added
Dec 22, 2025
This funding opportunity provides financial support to organizations that deliver comprehensive HIV care and essential services for women, infants, children, and youth affected by HIV in designated geographic areas.
Application Deadline
Nov 17, 2025
Date Added
Nov 13, 2024
This funding opportunity provides financial support to small businesses in the U.S. for conducting exploratory clinical trials or biomarker validation studies aimed at advancing therapies for neurological disorders.

