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Grants for Small businesses - Federal

Explore 1,841 grant opportunities

Measurement Science and Engineering (MSE) Research Grant Programs
$12,000,000
U.S. Department of Commerce (National Institute of Standards and Technology)
Federal

Application Deadline

Sep 15, 2026

Date Added

May 15, 2025

This funding opportunity provides financial support for a wide range of research and collaborative projects in measurement science and engineering, targeting universities, nonprofits, and businesses to enhance innovation and competitiveness in various technical fields.

Science and Technology
Nonprofits
Thermal Transport Processes
$7,047,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 5, 2023

This program provides funding for researchers to explore and advance the understanding of thermal transport phenomena, encouraging innovative approaches that integrate theory, experimentation, and numerical modeling across various scientific and engineering disciplines.

Science and Technology
For profit organizations other than small businesses
High-performance Optimized Recycled Nuclear Isotopes for Gen IV reactors (HORNIG)
$7,000,000
U.S. Department of Energy (Advanced Research Projects Agency Energy )
Federal

Application Deadline

Aug 6, 2026

Date Added

Apr 24, 2026

This funding opportunity provides financial support for U.S. institutions and organizations to develop advanced nuclear fuel technologies that utilize recycled materials, aiming to enhance energy security and reduce nuclear waste.

Opportunity Zone Benefits
Public and State controlled institutions of higher education
Army Research Lab Broad Agency Announcement (BAA) – Electrochemistry (Topic ID: ARL-BAA-0025)
Contact for amount
Army Research Laboratory
Federal

Application Deadline

Nov 20, 2027

Date Added

Mar 18, 2025

This funding opportunity is designed for researchers and institutions focused on advancing electrochemical science, particularly in areas like redox chemistry, electrocatalysis, and the transport of electroactive species, to develop innovative solutions and technologies.

Science and Technology
Public and State controlled institutions of higher education
Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 15, 2027

Date Added

Oct 30, 2024

This funding opportunity supports U.S.-based researchers and institutions in developing innovative computational methods for automating the curation of large biomedical datasets to improve data accessibility and quality for scientific research.

Education
State governments
Engineering Biological and Biomedical Systems (EBBS)
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 27, 2026

This program provides funding for researchers and organizations to explore innovative engineering solutions that enhance our understanding and manipulation of biological systems, ultimately aiming to improve human health and advance biotechnology.

Science and Technology
Public and State controlled institutions of higher education
Army Applications Lab Broad Agency Announcement For Disruptive Applications
Contact for amount
U.S. Department of Defense (Dept of the Army -- Materiel Command)
Federal

Application Deadline

Apr 4, 2029

Date Added

Jun 27, 2024

This grant provides funding for innovative research proposals from universities, non-profits, and businesses to develop disruptive technologies that enhance the U.S. Army's capabilities for future operations.

Science and Technology
Public and State controlled institutions of higher education
DoW Melanoma Research Program Focused Program Award Rare Melanomas
$2,800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 14, 2026

Date Added

May 6, 2026

This funding opportunity supports collaborative research projects focused on improving outcomes for rare melanoma subtypes, specifically targeting innovative prevention, detection, treatment, and survivorship strategies, with an emphasis on military health and patient-centered priorities.

Health
Nonprofits
DoW Breast Cancer, Breakthrough Award Level 4
$21,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 30, 2026

Date Added

May 5, 2026

This funding opportunity supports large-scale clinical research projects aimed at transforming breast cancer prevention and treatment, specifically targeting innovative trials that can significantly improve patient care and outcomes.

Health
Nonprofits
Nanoscale Interactions
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 5, 2023

This grant supports researchers exploring how nanomaterials interact with biological and environmental systems, aiming to advance sustainable engineering solutions and innovative materials design.

Science and Technology
Private institutions of higher education
United States Army Research Institute For The Behavioral And Social Sciences (Ari) Broad Agency Announcement For Basic, Applied, And Advanced Scientific Research
Contact for amount
U.S. Department of Defense (Dept of the Army -- Materiel Command)
Federal

Application Deadline

Apr 30, 2028

Date Added

May 1, 2023

This funding opportunity supports a wide range of behavioral and social science research aimed at enhancing the effectiveness and readiness of the U.S. Army, inviting proposals from universities, nonprofits, and private organizations.

Science and Technology
Nonprofits
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 5, 2027

Date Added

Jun 19, 2025

This funding opportunity supports U.S.-based small businesses partnering with nonprofit research institutions to develop and commercialize innovative health-related technologies through research and development activities.

Health
Small businesses
Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)
$450,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 21, 2026

Date Added

Jun 3, 2025

This funding opportunity supports research projects that aim to improve health outcomes for Native American, Alaska Native, and Native Hawaiian communities through culturally relevant interventions and strong community partnerships.

Education
State governments
2027 Emerging Markets Program
$500,000
U.S. Department of Agriculture (Foreign Agricultural Service)
Federal

Application Deadline

Aug 14, 2026

Date Added

Jun 11, 2026

This grant provides funding to U.S. organizations to develop and expand agricultural export markets in low- and middle-income countries through market assessments, technical assistance, and training initiatives.

Agriculture
Nonprofits
Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Administrative Resource (U24 Clinical Trials Optional)
$350,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 1, 2026

Date Added

May 23, 2025

This funding opportunity supports research initiatives aimed at understanding the effects of adolescent alcohol consumption on brain development and mental health, inviting a diverse range of eligible applicants, including educational institutions and nonprofits, to contribute to this important study.

Health
State governments
Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)
$275,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 2, 2027

Date Added

Dec 9, 2024

This funding opportunity provides financial support for researchers and organizations to conduct preclinical studies that demonstrate the effectiveness of potential treatments for rare diseases, ultimately aiming to advance these therapies toward clinical trials.

Health
Public and State controlled institutions of higher education
Defense Logistics Information Research (DLIR) Broad Agency Announcement (BAA-0002-21)
Contact for amount
Defense Logistics Agency (DLA), Department of Defense (DoD)
Federal
Rolling

Application Deadline

Dec 30, 2026

Date Added

Mar 20, 2025

This funding opportunity supports innovative research and development projects that enhance supply chain resilience and technical data management for organizations contributing to the Department of Defense's modernization efforts.

Information and Statistics
For profit organizations other than small businesses
NIDCD's Mentored Research Education Pathway for Otolaryngology Residents and Medical Students (R25 - Clinical Trial Not Allowed)
$499,999
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 29, 2026

Date Added

Apr 3, 2025

This funding opportunity supports U.S. medical students and otolaryngology residents in pursuing research education and mentorship to foster careers in biomedical and clinical research related to communication disorders.

Health
State governments
Home Study and Post-Release Services for Unaccompanied Alien Children
$50,000,000
U.S. Department of Health and Human Services (Administration for Children and Families - ORR)
Federal

Application Deadline

Oct 1, 2027

Date Added

Apr 9, 2026

This funding opportunity provides financial support to organizations that deliver home study assessments and post-release services for unaccompanied children in the U.S., ensuring their safety, well-being, and successful integration into communities.

Income Security and Social Services
Nonprofits
Foundations
$2,300,000
National Science Foundation
Federal

Application Deadline

Sep 22, 2026

Date Added

Oct 10, 2024

This program provides funding for researchers in mathematical logic to support innovative projects and academic events that advance the foundations of mathematics.

Science and Technology
City or township governments