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Grants for Small businesses - Federal

Explore 1,747 grant opportunities

Nanoscale Interactions
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 5, 2023

This grant supports researchers exploring how nanomaterials interact with biological and environmental systems, aiming to advance sustainable engineering solutions and innovative materials design.

Science and Technology
Private institutions of higher education
Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3 Clinical Trial Required)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 22, 2026

Date Added

Oct 31, 2024

This funding opportunity supports higher education institutions, nonprofits, small businesses, local governments, and tribal entities in conducting multi-site clinical trials to evaluate the effectiveness of natural products for various health conditions.

Health
State governments
Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)
$450,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 21, 2026

Date Added

Jun 3, 2025

This funding opportunity supports research projects that aim to improve health outcomes for Native American, Alaska Native, and Native Hawaiian communities through culturally relevant interventions and strong community partnerships.

Education
State governments
Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Administrative Resource (U24 Clinical Trials Optional)
$350,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 1, 2026

Date Added

May 23, 2025

This funding opportunity supports research initiatives aimed at understanding the effects of adolescent alcohol consumption on brain development and mental health, inviting a diverse range of eligible applicants, including educational institutions and nonprofits, to contribute to this important study.

Health
State governments
Defense Logistics Information Research (DLIR) Broad Agency Announcement (BAA-0002-21)
Contact for amount
Defense Logistics Agency (DLA), Department of Defense (DoD)
Federal
Rolling

Application Deadline

Dec 30, 2026

Date Added

Mar 20, 2025

This funding opportunity supports innovative research and development projects that enhance supply chain resilience and technical data management for organizations contributing to the Department of Defense's modernization efforts.

Information and Statistics
For profit organizations other than small businesses
NIDCD's Mentored Research Education Pathway for Otolaryngology Residents and Medical Students (R25 - Clinical Trial Not Allowed)
$499,999
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 29, 2026

Date Added

Apr 3, 2025

This funding opportunity supports U.S. medical students and otolaryngology residents in pursuing research education and mentorship to foster careers in biomedical and clinical research related to communication disorders.

Health
State governments
Foundations
$2,300,000
National Science Foundation
Federal

Application Deadline

Sep 22, 2026

Date Added

Oct 10, 2024

This program provides funding for researchers in mathematical logic to support innovative projects and academic events that advance the foundations of mathematics.

Science and Technology
City or township governments
DoW Pancreatic Cancer Research Program, Translational Research Partnership Award
$1,100,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 7, 2026

Date Added

May 5, 2026

This funding opportunity supports collaborative research projects aimed at advancing pancreatic cancer treatment and prevention by fostering partnerships between scientists and clinicians with expertise in the field.

Health
Nonprofits
Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 14, 2026

Date Added

Oct 16, 2024

Assay Validation of High Quality Markers for Clinical Studies in Cancer aims to fund the validation of reliable molecular, cellular, or imaging markers for cancer detection, diagnosis, and treatment, ensuring they meet necessary performance standards for use in clinical trials and studies.

Education
State governments
Facilities for Atmospheric Research and Education
$667,102,909
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Mar 8, 2022

This program provides access to advanced research facilities and instruments for scientists conducting atmospheric research, enabling impactful studies and fieldwork in the geosciences.

Science and Technology
For profit organizations other than small businesses
Windows On The Universe: The Era Of Multi-Messenger Astrophysics
Contact for amount
National Science Foundation
Federal

Application Deadline

Sep 30, 2026

Date Added

Dec 18, 2024

This program provides funding for researchers in astrophysics to conduct innovative studies that combine observations from different cosmic messengers, such as light, gravitational waves, and high-energy particles, to deepen our understanding of the universe.

Science and Technology
Public and State controlled institutions of higher education
DoD Lung Cancer Idea Development Award
$800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 2, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at reducing lung cancer deaths and suffering, particularly those that involve military or Veteran populations, by providing up to $800,000 for early-stage studies in various areas of lung cancer research.

Science and Technology
Nonprofits
DoW Spinal Cord Injury, Investigator-Initiated Research Award
$960,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 12, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research aimed at improving care and outcomes for individuals with spinal cord injuries, including military Service Members, Veterans, and civilians.

Health
Nonprofits
NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 15, 2027

Date Added

Oct 21, 2024

This funding opportunity supports early career researchers in the U.S. to conduct exploratory studies in areas related to hearing, communication, and sensory disorders, helping them gather preliminary data for future larger grant applications.

Health
State governments
Seeding Critical Advances For Leading Energy Technologies With Untapped Potential (SCALEUP) Ready
$20,000,000
U.S. Department of Energy (Advanced Research Projects Agency Energy)
Federal

Application Deadline

Sep 29, 2029

Date Added

Oct 3, 2024

This program provides funding to teams developing innovative energy technologies that have previously received ARPA-E support, helping them scale their projects for commercial viability and competitiveness in the global market.

Opportunity Zone Benefits
For profit organizations other than small businesses
Housing Policy Research Grant Notice of Funding Opportunity
$1,500,000
U.S. Department of Housing and Urban Development
Federal

Application Deadline

Jun 1, 2026

Date Added

Apr 22, 2026

This funding opportunity provides financial support for organizations conducting research on housing affordability, homelessness, and economic development in the U.S., aiming to generate actionable insights for policymakers and communities.

Housing
State governments
ROSES25: A.11 Early Career Investigator Program in Earth Science
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Jun 17, 2026

Date Added

Apr 20, 2026

This funding opportunity supports early career scientists in the U.S. to develop independent research projects that advance NASA's Earth science objectives.

Science and Technology
Public and State controlled institutions of higher education
Catalyze: Product Definition for Small Molecules, Biologics, and Combination Products - Preliminary Product/Lead Series Identification and Combination Product Prototype (R33 - Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 18, 2026

Date Added

Nov 25, 2024

This funding opportunity provides financial support for researchers and organizations to develop and prototype new small molecules, biologics, and combination products aimed at addressing heart, lung, blood, and sleep disorders.

Health
Public and State controlled institutions of higher education
Geospatial Intelligence Processing And Exploitation (Geopex)
$10,000,000
U.S. Department of Defense
Federal

Application Deadline

Sep 30, 2026

Date Added

Sep 22, 2025

This grant provides funding for research and development of technologies that enhance geospatial intelligence capabilities, targeting organizations and companies involved in imagery analysis and geospatial data solutions.

Science and Technology
For profit organizations other than small businesses
Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)
$85,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 7, 2028

Date Added

Jul 20, 2025

This funding opportunity provides small grants to early-career researchers who have received specific NHLBI career development awards, helping them advance their independent research in heart, lung, blood, and sleep health.

Health
Public and State controlled institutions of higher education