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Grants for Small businesses - Federal

Explore 1,841 grant opportunities

DoW Pancreatic Cancer Research Program, Translational Research Partnership Award
$1,100,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 7, 2026

Date Added

May 5, 2026

This funding opportunity supports collaborative research projects aimed at advancing pancreatic cancer treatment and prevention by fostering partnerships between scientists and clinicians with expertise in the field.

Health
Nonprofits
Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 14, 2026

Date Added

Oct 16, 2024

Assay Validation of High Quality Markers for Clinical Studies in Cancer aims to fund the validation of reliable molecular, cellular, or imaging markers for cancer detection, diagnosis, and treatment, ensuring they meet necessary performance standards for use in clinical trials and studies.

Education
State governments
Facilities for Atmospheric Research and Education
$667,102,909
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Mar 8, 2022

This program provides access to advanced research facilities and instruments for scientists conducting atmospheric research, enabling impactful studies and fieldwork in the geosciences.

Science and Technology
For profit organizations other than small businesses
Windows On The Universe: The Era Of Multi-Messenger Astrophysics
Contact for amount
National Science Foundation
Federal

Application Deadline

Sep 30, 2026

Date Added

Dec 18, 2024

This program provides funding for researchers in astrophysics to conduct innovative studies that combine observations from different cosmic messengers, such as light, gravitational waves, and high-energy particles, to deepen our understanding of the universe.

Science and Technology
Public and State controlled institutions of higher education
DoD Lung Cancer Idea Development Award
$800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 2, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at reducing lung cancer deaths and suffering, particularly those that involve military or Veteran populations, by providing up to $800,000 for early-stage studies in various areas of lung cancer research.

Science and Technology
Nonprofits
DoW Spinal Cord Injury, Investigator-Initiated Research Award
$960,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 12, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research aimed at improving care and outcomes for individuals with spinal cord injuries, including military Service Members, Veterans, and civilians.

Health
Nonprofits
Disability and Rehabilitation Research Projects (DRRP) Program: Americans with Disabilities Act (ADA) National Network Knowledge Translation Center
$850,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Jul 23, 2026

Date Added

Apr 23, 2026

This funding opportunity provides financial support to organizations that will enhance the understanding and implementation of the Americans with Disabilities Act by developing resources, conducting research, and facilitating training for various stakeholders.

Science and Technology
State governments
DoW Rare Cancers Concept Award
$140,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 30, 2026

Date Added

Jun 18, 2026

This funding opportunity supports innovative research projects aimed at improving outcomes for patients with rare cancers, particularly benefiting service members, veterans, and the general public.

Science and Technology
Nonprofits
NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 15, 2027

Date Added

Oct 21, 2024

This funding opportunity supports early career researchers in the U.S. to conduct exploratory studies in areas related to hearing, communication, and sensory disorders, helping them gather preliminary data for future larger grant applications.

Health
State governments
Electrochemical Systems
$13,096,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 5, 2023

This grant provides funding for researchers to develop innovative and sustainable electrochemical and photochemical systems that improve energy efficiency and environmental sustainability in producing electricity, fuels, and chemicals.

Science and Technology
Public and State controlled institutions of higher education
Seeding Critical Advances For Leading Energy Technologies With Untapped Potential (SCALEUP) Ready
$20,000,000
U.S. Department of Energy (Advanced Research Projects Agency Energy)
Federal

Application Deadline

Sep 29, 2029

Date Added

Oct 3, 2024

This program provides funding to teams developing innovative energy technologies that have previously received ARPA-E support, helping them scale their projects for commercial viability and competitiveness in the global market.

Opportunity Zone Benefits
For profit organizations other than small businesses
Housing Policy Research Grant Notice of Funding Opportunity
$1,500,000
U.S. Department of Housing and Urban Development
Federal

Application Deadline

Jul 20, 2026

Date Added

Apr 22, 2026

This funding opportunity provides financial support for research projects that address critical housing issues, such as affordability and homelessness, aimed at helping policymakers and practitioners improve housing policies across the United States.

Science and Technology
State governments
Ensuring Research Integrity Conferences and Workshops Program (CWP)
$50,000
U.S. Department of Health and Human Services (Office of the Assistant Secretary for Health)
Federal

Application Deadline

Jul 27, 2026

Date Added

Jun 26, 2026

This funding opportunity provides financial support for organizing conferences and workshops that promote research integrity and compliance with federal regulations in biomedical and behavioral research.

Science and Technology
State governments
Pax Silica Artificial Intelligence Assistance Project
$50,000,000
U.S. Department of State (Bureau of Economic and Business Affairs)
Federal

Application Deadline

Aug 20, 2026

Date Added

Jul 2, 2026

This funding opportunity provides substantial financial support for U.S.-based organizations to develop a secure platform that enhances the traceability and security of artificial intelligence supply chains, starting in Panama and potentially expanding to other partner countries.

Business and Commerce
Nonprofits
Catalyze: Product Definition for Small Molecules, Biologics, and Combination Products - Preliminary Product/Lead Series Identification and Combination Product Prototype (R33 - Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 21, 2027

Date Added

Nov 25, 2024

This funding opportunity provides financial support for researchers and organizations to develop and prototype new small molecules, biologics, and combination products aimed at addressing heart, lung, blood, and sleep disorders.

Health
Public and State controlled institutions of higher education
Geospatial Intelligence Processing And Exploitation (Geopex)
$10,000,000
U.S. Department of Defense
Federal

Application Deadline

Sep 30, 2026

Date Added

Sep 22, 2025

This grant provides funding for research and development of technologies that enhance geospatial intelligence capabilities, targeting organizations and companies involved in imagery analysis and geospatial data solutions.

Science and Technology
For profit organizations other than small businesses
DoW Kidney Cancer, Idea Development Award
$1,200,000
U.S. Department of Defense (Defense Health Agency Contracting Activity - DHACA)
Federal

Application Deadline

Sep 28, 2026

Date Added

Jun 19, 2026

This funding opportunity supports innovative research projects aimed at advancing the understanding, diagnosis, treatment, and patient care of kidney cancer, targeting both individual researchers and collaborative teams.

Science and Technology
Nonprofits
Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)
$85,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 7, 2028

Date Added

Jul 20, 2025

This funding opportunity provides small grants to early-career researchers who have received specific NHLBI career development awards, helping them advance their independent research in heart, lung, blood, and sleep health.

Health
Public and State controlled institutions of higher education
Rfa-Ce-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides financial support for a wide range of organizations, including state governments, universities, and nonprofits, to conduct research and initiatives focused on preventing injuries and improving community health.

Health
State governments
Needipedia Broad Agency Announcement
Contact for amount
Defense Intelligence Agency (DIA)
Federal
Rolling

Application Deadline

Dec 26, 2028

Date Added

Mar 20, 2025

This funding initiative invites businesses, academic institutions, and nonprofits to propose innovative solutions that address intelligence and defense needs for potential future support from the Defense Intelligence Agency.

Science and Technology
For profit organizations other than small businesses