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Grants for Small businesses - Federal

Explore 1,962 grant opportunities

DoW Spinal Cord Injury, Investigator-Initiated Research Award
$960,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 12, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research aimed at improving care and outcomes for individuals with spinal cord injuries, including military Service Members, Veterans, and civilians.

Health
Nonprofits
DoW Rare Cancers Concept Award
$140,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 30, 2026

Date Added

Jun 18, 2026

This funding opportunity supports innovative research projects aimed at improving outcomes for patients with rare cancers, particularly benefiting service members, veterans, and the general public.

Science and Technology
Nonprofits
NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 15, 2027

Date Added

Oct 21, 2024

This funding opportunity supports early career researchers in the U.S. to conduct exploratory studies in areas related to hearing, communication, and sensory disorders, helping them gather preliminary data for future larger grant applications.

Health
State governments
Seeding Critical Advances For Leading Energy Technologies With Untapped Potential (SCALEUP) Ready
$20,000,000
U.S. Department of Energy (Advanced Research Projects Agency Energy)
Federal

Application Deadline

Sep 29, 2029

Date Added

Oct 3, 2024

This program provides funding to teams developing innovative energy technologies that have previously received ARPA-E support, helping them scale their projects for commercial viability and competitiveness in the global market.

Opportunity Zone Benefits
For profit organizations other than small businesses
Catalyze: Product Definition for Small Molecules, Biologics, and Combination Products - Preliminary Product/Lead Series Identification and Combination Product Prototype (R33 - Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 21, 2027

Date Added

Nov 25, 2024

This funding opportunity provides financial support for researchers and organizations to develop and prototype new small molecules, biologics, and combination products aimed at addressing heart, lung, blood, and sleep disorders.

Health
Public and State controlled institutions of higher education
Geospatial Intelligence Processing And Exploitation (Geopex)
$10,000,000
U.S. Department of Defense
Federal

Application Deadline

Sep 30, 2026

Date Added

Sep 22, 2025

This grant provides funding for research and development of technologies that enhance geospatial intelligence capabilities, targeting organizations and companies involved in imagery analysis and geospatial data solutions.

Science and Technology
For profit organizations other than small businesses
DoW Kidney Cancer, Idea Development Award
$1,200,000
U.S. Department of Defense (Defense Health Agency Contracting Activity - DHACA)
Federal

Application Deadline

Sep 28, 2026

Date Added

Jun 19, 2026

This funding opportunity supports innovative research projects aimed at advancing the understanding, diagnosis, treatment, and patient care of kidney cancer, targeting both individual researchers and collaborative teams.

Science and Technology
Nonprofits
Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)
$170,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 7, 2028

Date Added

Jul 20, 2025

This funding opportunity provides financial support to researchers who have recently completed or are currently holding specific NIH career development awards, enabling them to advance their independent research projects in heart, lung, and blood diseases.

Health
Public and State controlled institutions of higher education
Rfa-Ce-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides financial support for a wide range of organizations, including state governments, universities, and nonprofits, to conduct research and initiatives focused on preventing injuries and improving community health.

Health
State governments
Needipedia Broad Agency Announcement
Contact for amount
Defense Intelligence Agency (DIA)
Federal
Rolling

Application Deadline

Dec 26, 2028

Date Added

Mar 20, 2025

This funding initiative invites businesses, academic institutions, and nonprofits to propose innovative solutions that address intelligence and defense needs for potential future support from the Defense Intelligence Agency.

Science and Technology
For profit organizations other than small businesses
2026 Alaska Marine Education and Training Mini-Grant Program
$75,000
U.S. Department of Commerce (National Oceanic and Atmospheric Administration)
Federal

Application Deadline

May 1, 2028

Date Added

Apr 24, 2026

This funding opportunity provides financial support for projects that enhance marine education, workforce development, and sustainability initiatives in Alaska's coastal communities.

Workforce Development
Individuals
ERDC Broad Agency Announcement
$999,999,999
U.S. Department of Defense (Engineer Research and Development Center)
Federal

Application Deadline

Jan 1, 2027

Date Added

Jan 5, 2026

This funding opportunity supports innovative research and development projects in various scientific and engineering fields, particularly those that align with military and civil missions, and encourages collaboration among universities, non-profits, and small businesses, including participation from minority institutions.

Science and Technology
Public and State controlled institutions of higher education
Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
$50,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 16, 2027

Date Added

Oct 31, 2024

This funding opportunity provides financial support for small-scale research projects that aim to improve the adoption and sustainability of evidence-based health practices, particularly in underserved communities, by addressing barriers and engaging diverse stakeholders.

Education
State governments
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 30, 2028

Date Added

Aug 28, 2025

This funding opportunity provides additional financial support to current NIH grant recipients for unforeseen expenses necessary to complete their existing research projects without expanding their original scope.

Health
State governments
DoD, Ovarian Cancer, Pilot Award
$350,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 1, 2026

Date Added

May 5, 2026

This funding opportunity supports innovative early-stage research projects aimed at improving the prevention, detection, treatment, and survivorship of ovarian cancer, particularly benefiting service members, veterans, and their families.

Health
Nonprofits
FY26 Bus Safety, Accessibility, and Innovation Notice of Funding Opportunity
$10,000,000
U.S. Department of Transportation (DOT - Federal Transit Administration)
Federal

Application Deadline

Sep 28, 2026

Date Added

Jul 30, 2026

This funding opportunity provides financial support for research and projects focused on improving bus safety, accessibility, and innovation across various organizations involved in public transportation.

Transportation
State governments
Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)
$150,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 14, 2026

Date Added

Oct 11, 2024

This funding opportunity is designed for researchers with active NCI R01 grants to validate and enhance existing cancer biomarker assays, facilitating their clinical use and improving cancer detection and treatment strategies.

Health
Public and State controlled institutions of higher education
Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 25, 2027

Date Added

Jun 3, 2026

This funding opportunity supports a network of research centers dedicated to studying how cancer patients respond to radiation therapy, aiming to improve treatment outcomes through collaborative, multidisciplinary research.

Health
Public and State controlled institutions of higher education
Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed)
$20,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 28, 2026

Date Added

Jun 10, 2025

This funding opportunity supports researchers in developing and sharing innovative biological models and tools that enhance understanding of human health and diseases across multiple biomedical fields.

Health
Public and State controlled institutions of higher education
DoW Toxic Exposures Clinical Trial Award
$4,500,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 19, 2026

Date Added

May 8, 2026

This funding opportunity supports clinical trials aimed at addressing health issues related to military-related toxic exposures, targeting researchers and organizations focused on improving the health of Service Members, Veterans, and their families.

Health
Nonprofits