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Grants for Small businesses - Federal

Explore 1,747 grant opportunities

DoW Amyotrophic Lateral Sclerosis Research Program, Pilot Clinical Trial Award
$2,800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 30, 2026

Date Added

May 5, 2026

This funding opportunity supports pilot clinical trials aimed at improving treatment and care for individuals with amyotrophic lateral sclerosis (ALS), emphasizing collaboration with patients and their families.

Health
Nonprofits
NIJ FY25 Research and Evaluation of Policing Practices
$5,000,000
U.S. Department of Justice (National Institute of Justice)
Federal

Application Deadline

Jun 9, 2026

Date Added

May 8, 2026

This funding opportunity provides financial support for research and evaluation projects aimed at improving policing practices, officer well-being, and public safety outcomes across various law enforcement agencies in the United States.

Law Justice and Legal Services
State governments
Harmful Algal Bloom Innovation Challenge: Toxin Detection in Seafood
$250,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Jul 16, 2026

Date Added

Mar 16, 2026

This funding opportunity provides financial support for U.S. institutions and organizations to develop innovative and cost-effective technologies for detecting harmful algal bloom toxins in seafood, enhancing public health and seafood safety.

Environment
Nonprofits
Science of Science: Discovery, Communication and Impact
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

May 9, 2025

This grant provides funding for researchers to explore and improve the processes of scientific discovery, communication, and its impact on society, with a focus on innovative and transformative approaches.

Science and Technology
Nonprofits
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)
$750,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 20, 2027

Date Added

Oct 23, 2024

This funding opportunity provides financial support for research institutions and organizations to develop and validate innovative model systems that can improve the discovery of new treatments for neurological and neuromuscular disorders.

Health
State governments
CHIPS Research and Development Office (CRDO) Broad Agency Announcement (BAA)
Contact for amount
U.S. Department of Commerce (National Institute of Standards and Technology)
Federal

Application Deadline

Sep 30, 2029

Date Added

Sep 25, 2025

This funding opportunity supports U.S.-based organizations in advancing semiconductor technologies and innovation to strengthen the domestic semiconductor ecosystem and enhance national security.

Science and Technology
For profit organizations other than small businesses
ROSES 2025: C.2 Solar System Science
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Aug 1, 2026

Date Added

Jul 12, 2025

This grant provides funding for researchers at U.S.-based institutions to conduct innovative studies that enhance our understanding of planetary science and the solar system.

Science and Technology
Public and State controlled institutions of higher education
DoW Amyotrophic Lateral Sclerosis Research Program, Therapeutic Development Award
$2,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 30, 2026

Date Added

May 5, 2026

This funding opportunity supports research projects that advance promising therapeutic candidates for amyotrophic lateral sclerosis (ALS) from preclinical stages to readiness for clinical trials, emphasizing the development of effective treatments and relevant biomarkers.

Health
Nonprofits
BRAIN Initiative: Production and distribution facilities for brain cell type-specific access reagents (U24 Clinical Trial Not Allowed)
$2,400,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 1, 2026

Date Added

Feb 21, 2024

This funding opportunity supports the establishment of facilities that will produce and distribute specialized brain cell access tools for neuroscience research, enabling scientists to better study and manipulate specific brain cell types.

Health
Public and State controlled institutions of higher education
BROAD AGENCY ANNOUNCEMENT (BAA) for Extramural Biomedical and Human Performance Research and Development Department of Defense
$10,000,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Jul 31, 2028

Date Added

Jul 27, 2023

This funding opportunity supports research projects that improve medical and human performance capabilities for military personnel, focusing on innovative solutions for Special Operations Forces in challenging environments.

Health
Nonprofits
Engineering for Civil Infrastructure
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jun 12, 2018

This funding initiative provides support for researchers in civil engineering to develop innovative solutions that enhance the sustainability and resilience of the nation’s infrastructure systems against climate change and natural hazards.

Science and Technology
Public and State controlled institutions of higher education
Alfalfa Seed and Alfalfa Forage Systems
$900,000
U.S. Department of Agriculture (National Institute of Food and Agriculture)
Federal

Application Deadline

Jun 12, 2026

Date Added

Apr 29, 2026

This program provides funding to support research and extension projects that improve alfalfa seed and forage production systems, benefiting farmers, ranchers, and agricultural institutions across the U.S.

Agriculture
Public and State controlled institutions of higher education
Advanced Cyber Effects for Strategic Operations
$99,980,000
U.S. Department of Defense
Federal

Application Deadline

Jul 10, 2030

Date Added

Sep 29, 2025

This grant provides funding for innovative research and development of cyber operations prototypes to enhance the U.S. Department of Defense's capabilities in the cyber domain, targeting a wide range of eligible applicants including universities, businesses, and research organizations.

Science and Technology
For profit organizations other than small businesses
Bioengineering Partnerships with Industry (U01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 27, 2026

Date Added

Nov 7, 2024

This funding opportunity supports collaborations between academic institutions and industry partners to develop innovative bioengineering technologies that address critical biomedical challenges over a 5-10 year period.

Education
State governments
Energy Frontier Research Centers (EFRCs)
$18,000,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

Jul 1, 2026

Date Added

Feb 18, 2026

This funding opportunity supports interdisciplinary research teams in the U.S. to conduct foundational studies in energy, environment, and national security, fostering scientific innovation and training the next generation of energy-focused researchers.

Science and Technology
State governments
Defense Sciences Office (DSO) Office-wide BAA
Contact for amount
U.S. Department of Defense (DARPA - Defense Sciences Office)
Federal

Application Deadline

Jun 2, 2026

Date Added

Jun 4, 2025

This grant provides funding for innovative research proposals that advance scientific and technological breakthroughs to enhance national security, targeting a wide range of applicants including private institutions, nonprofits, and small businesses.

Science and Technology
For profit organizations other than small businesses
Metal Casting BAA0001-21
Contact for amount
Defense Logistics Agency (DLA), Department of Defense (DoD)
Federal

Application Deadline

Jun 30, 2026

Date Added

Mar 20, 2025

This funding opportunity supports research and development in metal casting technologies to enhance military applications and meet national defense needs.

Science and Technology
For profit organizations other than small businesses
Biosensing
$7,600,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Sep 12, 2019

This funding initiative supports researchers developing innovative biosensing technologies to monitor and identify biological substances, addressing critical challenges in health, agriculture, and environmental protection.

Science and Technology
Public and State controlled institutions of higher education
NSF National Quantum Virtual Laboratory - Quantum Testbeds
$10,000,000
National Science Foundation
Federal

Application Deadline

Apr 6, 2027

Date Added

May 14, 2025

This funding opportunity supports large-scale projects that advance quantum technology through collaborative research and development among academia, industry, and government, specifically targeting the design and implementation of scalable quantum systems.

Science and Technology
Public and State controlled institutions of higher education
UNITED STATES MILITARY ACADEMY Broad Agency Announcement
Contact for amount
U.S. Department of Defense (Dept of the Army -- Materiel Command)
Federal

Application Deadline

Mar 31, 2027

Date Added

May 28, 2025

This funding opportunity supports innovative research proposals from a wide range of organizations to advance military capabilities and address critical challenges facing the Army and the nation.

Science and Technology
Public and State controlled institutions of higher education