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Grants for Small businesses - Federal

Explore 1,962 grant opportunities

Coupling, Energetics, and Dynamics of Atmospheric Regions
$750,000
National Science Foundation
Federal

Application Deadline

Mar 3, 2027

Date Added

Mar 21, 2025

This funding opportunity supports U.S.-based educational institutions, research organizations, and qualified entities in conducting innovative research on the dynamics and interactions of Earth's upper atmosphere and its relationship with other planetary atmospheres.

Science and Technology
Public and State controlled institutions of higher education
Plant Protection Act Section 7721 Plant Pest and Disease Management and Disaster Prevention Program (PPDMDPP)
$400,000
U.S. Department of Agriculture (Animal and Plant Health Inspection Service)
Federal

Application Deadline

Sep 21, 2026

Date Added

Jul 28, 2026

This funding opportunity provides financial support for projects that enhance the detection and management of harmful plant pests and diseases, targeting a wide range of eligible applicants including state agencies, nonprofits, and educational institutions.

Agriculture
State governments
TIP Office International Programs to Combat Human Trafficking Annual Program Statement
$10,000,000
U.S. Department of State (Office to Monitor-Combat Trafficking in Persons)
Federal

Application Deadline

Sep 30, 2026

Date Added

Jun 19, 2026

This grant provides funding to organizations working internationally to combat human trafficking through initiatives focused on prosecuting traffickers, protecting victims, and preventing trafficking, particularly in the Western Hemisphere and East Asia and the Pacific Islands.

Safety
Nonprofits
Research Infrastructure in the Social and Behavioral Sciences
$2,000,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Oct 5, 2023

This program provides funding to develop innovative tools and data resources that enhance research capabilities in the social and behavioral sciences, benefiting researchers across various disciplines.

Science and Technology
City or township governments
Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)
$150,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 11, 2027

Date Added

Dec 31, 2024

This funding opportunity supports innovative research projects that aim to transform the understanding and treatment of substance use disorders, encouraging bold ideas from both addiction experts and researchers from other fields.

Education
State governments
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)
$275,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 16, 2027

Date Added

Dec 19, 2024

This funding opportunity supports innovative and high-risk research projects in biomedical and behavioral sciences, encouraging early-stage investigators and organizations to explore new ideas that could significantly advance human health.

Education
Public and State controlled institutions of higher education
US Army Combat Capabilities Development Command Broad Agency Announcement
Contact for amount
U.S. Department of Defense (ACC APG - Natick)
Federal

Application Deadline

Feb 27, 2030

Date Added

Jul 15, 2025

This funding opportunity supports innovative research and technological solutions for next-generation soldier technologies, targeting universities, nonprofit research institutions, and commercial firms, excluding government organizations.

Science and Technology
Public and State controlled institutions of higher education
Incorporating Human Behavior in Epidemiological Models (IHBEM)
$6,000,000
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Aug 20, 2026

The Incorporating Human Behavior in Epidemiological Models (IHBEM) program supports research that incorporates social and behavioral processes in mathematical epidemiological models. The program provides support for projects that involve integrated participation from the mathematical and social, behavioral, and economic sciences.

Science and Technology
Nonprofits
DoW Kidney Cancer, Academy of Kidney Cancer Investigators Early-Career Scholar Award
$1,200,000
U.S. Department of Defense (Defense Health Agency Contracting Activity - DHACA)
Federal

Application Deadline

Sep 28, 2026

Date Added

Jun 19, 2026

This funding opportunity supports early-career researchers in kidney cancer by providing substantial financial resources and mentorship to advance innovative research and foster their development into independent investigators.

Science and Technology
Public and State controlled institutions of higher education
Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions (U01 Clinical Trial Not Allowed)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 5, 2029

Date Added

Jul 30, 2025

This funding opportunity is designed to support innovative research on how human behaviors impact oral and systemic health in individuals with chronic conditions, encouraging collaborations among experts in health and social sciences.

Health
Public and State controlled institutions of higher education
Injury Prevention and Control Research and State and Community Based Programs - RFA-IP-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 20, 2023

This funding opportunity provides financial support for a variety of organizations, including states, universities, and nonprofits, to develop and implement research and community programs focused on preventing and controlling injuries.

Health
State governments
DoW Military Burn, Discovery Award
$200,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 21, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at improving burn care for military personnel, particularly those injured in combat or training, by providing financial resources for groundbreaking studies that can lead to significant advancements in treatment.

Health
Nonprofits
Logistics Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U24 Clinical Trials Not Allowed)
$2,500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 2, 2026

Date Added

Jun 7, 2025

This funding opportunity provides financial support to U.S.-based organizations for establishing a centralized center that will enhance collaboration and coordination in developing AI-driven tools that integrate imaging and multimodal health data for personalized medicine.

Health
Public and State controlled institutions of higher education
Small Business Innovation Research and Small Business Technology Transfer Phase I (Genesis Mission)
$256,500
U.S. Department of Energy (Office of Technology Commercialization)
Federal

Application Deadline

Sep 10, 2026

Date Added

Jul 24, 2026

This funding opportunity provides financial support to American small businesses developing innovative technologies in areas like biotechnology, artificial intelligence, and advanced materials to help advance scientific discovery and commercial viability.

Science and Technology
Small businesses
DoW Amyotrophic Lateral Sclerosis Research Program, Pilot Clinical Trial Award
$2,800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 30, 2026

Date Added

May 5, 2026

This funding opportunity supports early-phase clinical trials aimed at improving treatments and care for individuals living with ALS, inviting applications from a wide range of organizations, including academic and nonprofit entities.

Science and Technology
Nonprofits
DARRP Restoration Implementation Grants (2026)
$100,000,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Nov 18, 2026

Date Added

Sep 2, 2026

This funding opportunity provides financial support for institutions and organizations to implement marine and coastal habitat restoration projects aimed at addressing damages from oil spills and hazardous substance releases.

Natural Resources
Nonprofits
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)
$750,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 20, 2027

Date Added

Oct 23, 2024

This funding opportunity provides financial support for research institutions and organizations to develop and validate innovative model systems that can improve the discovery of new treatments for neurological and neuromuscular disorders.

Health
State governments
DoW Melanoma Research Program Team Science Award
$2,100,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 14, 2026

Date Added

May 6, 2026

This funding opportunity supports collaborative research teams working on innovative projects to improve prevention, understanding, and care related to melanoma, benefiting Service Members, Veterans, and the general public.

Health
Nonprofits
HEAL Initiative: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice (R61/R33 - Clinical Trial Optional)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 9, 2029

Date Added

Jun 5, 2026

This funding opportunity supports research projects that develop and implement effective strategies for preventing and treating addiction, particularly opioid use, in various community and healthcare settings across the U.S.

Health
Public and State controlled institutions of higher education
CHIPS Research and Development Office (CRDO) Broad Agency Announcement (BAA)
Contact for amount
U.S. Department of Commerce (National Institute of Standards and Technology)
Federal

Application Deadline

Sep 15, 2026

Date Added

Sep 25, 2025

This grant provides funding to U.S. organizations and institutions to advance semiconductor technology and innovation, enhancing the domestic semiconductor ecosystem and supporting national security.

Science and Technology
Nonprofits