Grants for Small businesses - Federal

This grant provides salary support for scientists with advanced degrees who contribute specialized expertise to NCI-funded cancer research programs within core facilities, promoting career stability without requiring independent investigator roles.

This funding opportunity supports small businesses in developing innovative tools and devices to improve the care and management of animals used in research, enhancing their welfare and the efficiency of research facilities.

This grant provides funding for research projects that investigate how social factors like race, income, and sexual orientation intersect to affect health disparities in U.S. populations, aiming to inform effective interventions and policies.

The FY24 PRMRP Clinical Trial Award supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of a disease or condition addressed in one of the congressionally directed FY24 PRMRP Topic Areas and FY24 PRMRP Strategic Goals. Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance, and/or emerging approaches and technologies. Proposed projects may range from small proof-of-concept trials (e.g., pilot, first in human, phase 0) to demonstrate the feasibility or inform the design of more advanced trials through large-scale phase 1 to phase 3 trials to determine efficacy in relevant patient populations.Applications from investigators within the military Services and applications involving multidisciplinary collaborations among academia, industry, the military Services, the U.S. Department of Veterans Affairs (VA), and other federal government agencies are highly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the collaborators bring to the research effort, ultimately advancing research that is of significance to Service Members, Veterans, and their Families. If the proposed research relies on access to unique resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research.CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in women's health outcomes and/or advancing knowledge for women's health.Funding from this award mechanism must support a clinical trial. A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes. Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.

This funding opportunity is designed for researchers and teams focused on improving our understanding of snow accumulation and ice flow dynamics in glaciers across the Northern Hemisphere, with an emphasis on airborne and ground-based observations, modeling, and data synthesis.

This funding opportunity provides financial support for a wide range of physics research projects at U.S. institutions, including universities and nonprofit organizations, to advance knowledge in various subfields of physics.

This funding opportunity is designed to support research institutions and organizations in developing innovative energetic materials and methods to enhance the Army's capabilities in weapon systems and multi-domain operations.

This funding opportunity supports small businesses in developing innovative medical products to help treat and diagnose individuals struggling with opioid and stimulant use disorders.

This grant provides funding for researchers to develop and validate innovative organ-on-a-chip technologies that model dental, oral, and craniofacial diseases, aiming to improve drug testing and reduce reliance on animal models.

The purpose of this Funding Opportunity Announcement (FOA) is to facilitate the transition of previously funded SBIR and STTR Phase II and Phase IIB projects in pain management to the commercialization stage by providing additional assistance for private partnering activities through the Commercialization Readiness Pilot (CRP) program. Specifically, this FOA supports the addition of entrepreneurial expertise into small business leadership teams along with supporting partnering activities to aid in commercialization through private third-party funding or partnership with industry.

This funding opportunity provides financial support for a variety of organizations to advance genomic research in pediatric cancers and congenital anomalies, fostering collaboration and innovation in understanding and treating these conditions.

This grant provides funding to organizations in South Africa to improve economic analysis and capacity for managing HIV, tuberculosis, and related health issues, ultimately enhancing public health program efficiency and resource allocation.

This funding opportunity supports U.S.-based small businesses in health-related fields to develop innovative technologies, with a focus on projects that can successfully transition to commercialization.

This funding opportunity provides financial support to organizations that aim to improve educational resources and public awareness for families affected by Creutzfeldt-Jakob disease and enhance national surveillance efforts for this rare neurological condition.

This funding opportunity provides support for U.S.-based organizations to develop and implement effective substance use prevention services within various community systems, targeting individuals at risk or already misusing substances.

To implement a project aimed at advancing U.S. foreign policy and national security priorities by supporting initiatives that is more reflective of and responsive to the needs and perspectives of partner states to ensure strategic trade control systems meet international standards and by engaging on bilateral, regional and multilateral levels with foreign governments to aid in the establishment of independent capabilities to regulate transfers of weapons of mass destruction, WMD-related items, conventional arms, and related dual-use items, and to detect, interdict, investigate, and prosecute illicit transfers of such items.

This funding opportunity supports innovative research into the biology and mechanisms of bladder cancer, particularly focusing on non-muscle-invasive bladder cancer, to improve understanding and develop new prevention or treatment strategies.

This funding opportunity provides financial support to organizations that help family treatment courts improve services for parents facing substance use and mental health challenges in child welfare cases.

Amendment 2 to the NASA ARMD Research Opportunities in Aeronautics (ROA) 2024 NRA has been posted on the NSPIRES web site. University Leadership Initiative (ULI) provides the opportunity for university teams to exercise technical and organizational leadership in proposing unique technical challenges in aeronautics, defining multi-disciplinary solutions, establishing peer review mechanisms, and applying innovative teaming strategies to strengthen the research impact.Research proposals are sought in six ULI topic areas in Appendix D.4.Topic 1: Safe, Efficient Growth in Global Operations (Strategic Thrust 1)Topic 2: Innovation in Commercial High-Speed Aircraft (Strategic Thrust 2)Topic 3: Ultra-Efficient Subsonic Transports (Strategic Thrust 3) Topic 4: Safe, Quiet, and Affordable Vertical Lift Air Vehicles (Strategic Thrust 4)Topic 5: In-Time System-Wide Safety Assurance (Strategic Thrust 5)Topic 6: Assured Autonomy for Aviation Transformation (Strategic Thrust 6)This NRA will utilize a two-step proposal submission and evaluation process. The initial step is a short mandatory Step-A proposal due May 29, 2024. Those offerors submitting the most highly rated Step-A proposals will be invited to submit a Step-B proposal. All proposals must be submitted electronically through NSPIRES at https://nspires.nasaprs.com.An Applicants Workshop will be held on Thursday Apr 3, 2024; 1:00-3:00 p.m. ET (https://uli.arc.nasa.gov/applicants-workshops/workshop8).An interested partners list for this ULI is at https://uli.arc.nasa.gov/partners. To be listed as an interested lead or partner, please send electronic mail to hq-univpartnerships@mail.nasa.gov with "ULI Partnerships" in the subject line and include the information required for the table in that web page.

This announcement seeks revolutionary research ideas for topics not being addressed by ongoing BTO programs or other published solicitations. This publication constitutes a Broad Agency Announcement (BAA) as contemplated in Federal Acquisition Regulation (FAR) 6.102(d)(2) and 35.016 and 2 CFR § 200.203. Any resultant award negotiations will follow all pertinent law and regulation, and any negotiations and/or awards for procurement contracts will use procedures under FAR 15.4, Contract Pricing, as specified in the BAA. BTO's mission is to develop capabilities that leverage the unique properties of biology - adaption, replication, resilience and complexity, to revolutionize how the United States defends the homeland and prepares and protects its Warfighters. Research in BTO creates biotechnological capabilities that provide tactical care and restore function to injured warfighters, increase operational resilience, develop novel functional materials, and detect and protect against threats to maintain force readiness.