Grants for Small businesses - Federal
Explore 1,859 grant opportunities
Application Deadline
Dec 9, 2025
Date Added
Sep 12, 2025
This funding opportunity provides financial support for a wide range of physics research projects at U.S. institutions, including universities and nonprofit organizations, to advance knowledge in various subfields of physics.
Application Deadline
Oct 30, 2025
Date Added
May 15, 2025
This funding opportunity provides financial support for a variety of organizations to advance genomic research in pediatric cancers and congenital anomalies, fostering collaboration and innovation in understanding and treating these conditions.
Application Deadline
Jun 22, 2026
Date Added
Oct 3, 2024
This funding opportunity supports U.S.-based institutions and organizations in validating candidate biomarkers for neurological and neuromuscular disorders to improve clinical decision-making and therapeutic development.
Application Deadline
Jun 22, 2026
Date Added
May 20, 2026
This program provides funding to educational institutions, flight schools, and organizations to develop training initiatives that address the national shortage of qualified pilots and unmanned aircraft systems operators.
Application Deadline
Not specified
Date Added
Jan 10, 2023
This funding opportunity supports early-stage researchers in the U.S. to develop expertise in using nonhuman primate models for biomedical research, with a focus on infectious diseases, neuroscience, and aging, through a structured mentorship program.
Application Deadline
Nov 17, 2025
Date Added
Mar 9, 2024
This funding opportunity supports small businesses in the U.S. to develop innovative technologies that improve health outcomes and reduce disparities for minority populations.
Application Deadline
May 14, 2026
Date Added
Feb 26, 2026
This funding opportunity provides financial support for U.S.-based organizations to conduct innovative geothermal energy field tests and resource assessments, aiming to expand geothermal energy production across the country.
Application Deadline
May 4, 2026
Date Added
Apr 1, 2026
This funding opportunity supports organizations in evaluating and improving data collection efforts related to sexual victimization in correctional facilities across the United States.
Application Deadline
May 28, 2026
Date Added
Apr 14, 2026
This funding opportunity supports the development of community partnerships to create cybersecurity training programs that address local workforce needs and prepare job-ready candidates in the U.S.
Application Deadline
Jul 6, 2026
Date Added
Nov 19, 2024
This funding opportunity supports innovative research projects aimed at improving drug therapies and precision medicine for pregnant individuals, breastfeeding mothers, neonates, and children, particularly those from underrepresented populations.
Application Deadline
Oct 15, 2025
Date Added
Mar 18, 2025
This funding opportunity supports innovative research proposals from small businesses, academic institutions, and research organizations to develop high-risk, high-reward microsystem technologies for defense applications.
Application Deadline
Jul 14, 2026
Date Added
Oct 31, 2024
This funding opportunity supports the establishment of a Data Coordinating Center to manage and oversee multi-site clinical trials evaluating the effectiveness of natural products, aimed at U.S.-based research institutions and organizations.
Application Deadline
Dec 9, 2025
Date Added
Sep 29, 2025
This grant provides funding to a diverse range of organizations, including businesses and research institutions, to develop energy-efficient machine learning technologies that can be applied in energy-constrained environments, particularly for national defense.
Application Deadline
Jul 8, 2026
Date Added
May 7, 2026
This funding opportunity provides financial support for organizations to conduct rapid data analysis and targeted research on rural health issues, helping improve healthcare access and quality in underserved rural areas across the United States.
Application Deadline
May 7, 2026
Date Added
Nov 26, 2024
This funding opportunity provides financial support for pilot studies that develop and test innovative interventions aimed at preventing HIV in populations significantly affected by alcohol use, such as men who have sex with men, sex workers, and individuals recently released from incarceration.
Application Deadline
Not specified
Date Added
Jun 7, 2025
This funding opportunity supports local organizations in underserved states and territories to implement educational programs that encourage youth aged 10 to 19 to avoid non-marital sexual activity and promote healthy life choices.
Application Deadline
Mar 10, 2026
Date Added
Oct 1, 2024
This funding opportunity supports research projects that investigate how mitochondrial function affects brain health and immune aging in individuals living with HIV and substance use disorders, aiming to identify new therapeutic strategies.
Application Deadline
Nov 3, 2025
Date Added
May 28, 2025
This funding opportunity is designed to support the establishment of research centers that provide essential resources and infrastructure for advancing studies on rheumatic diseases, encouraging collaboration among researchers and institutions.
Application Deadline
Feb 17, 2026
Date Added
Oct 17, 2025
This funding opportunity provides financial support to a wide range of organizations working to improve HIV treatment and care services in Sierra Leone, aiming to enhance healthcare delivery and strengthen local health systems.
Application Deadline
Dec 19, 2025
Date Added
Sep 29, 2025
This grant provides funding for multidisciplinary teams, including researchers, industry partners, and patient advocates, to develop innovative genetic therapies for rare hereditary diseases affecting millions of Americans, particularly children, by creating safe and effective one-time treatments.

