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Grants for Small businesses - Federal

Explore 1,747 grant opportunities

OSERS-OSEP: National Assessment Center
$1,000,000
U.S. Department of Education
Federal

Application Deadline

Jul 20, 2026

Date Added

May 21, 2026

This grant provides funding to various educational organizations and agencies to improve assessment participation and performance for children with disabilities across the nation.

Education
State governments
DoD Breast Cancer, Transformative Breast Cancer Consortium Award
$35,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 30, 2026

Date Added

May 5, 2026

This funding opportunity supports large-scale, collaborative research projects aimed at significantly advancing the understanding, prevention, and treatment of breast cancer, involving multiple institutions and disciplines.

Science and Technology
Nonprofits
Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2028

Date Added

Nov 1, 2024

This funding opportunity supports clinical trials that evaluate effective mental health interventions and services for individuals transitioning from acute care to long-term support, particularly for underserved populations.

Health
State governments
DoW Pancreatic Cancer Research Program, Idea Development Award
$700,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 7, 2026

Date Added

May 5, 2026

This funding opportunity supports innovative research projects aimed at improving early detection, treatment, and outcomes for individuals affected by pancreatic cancer, particularly benefiting Service Members, Veterans, and their families.

Health
Nonprofits
Strengthening Early Warning, Detection, Response in Mozambique
$2,960,039
U.S. Department of State (Bureau of Counterterrorism )
Federal

Application Deadline

Jun 9, 2026

Date Added

May 6, 2026

This funding opportunity provides financial support to organizations working to improve early warning systems and response capabilities against security threats in Cabo Delgado, Mozambique, enhancing collaboration between local law enforcement and communities to protect U.S. economic interests.

Law Justice and Legal Services
Nonprofits
NSF STEM K-12
$750,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Aug 23, 2025

This funding opportunity supports a wide range of projects aimed at improving STEM education and learning outcomes in schools and informal settings across the United States, targeting institutions, organizations, and individuals involved in education and research.

Education
Public and State controlled institutions of higher education
Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)
$600,000
U.S. Department of Health & Human Services (Food and Drug Administration)
Federal

Application Deadline

Feb 8, 2028

Date Added

Jul 12, 2025

This funding opportunity supports research projects that investigate the natural history of rare diseases, aiming to improve medical product development and patient outcomes through collaborative studies and innovative methodologies.

Health
Public and State controlled institutions of higher education
DEVCOM Analysis Center Broad Agency Announcement For Applied Research
Contact for amount
U.S. Department of Defense (Dept of the Army -- Materiel Command)
Federal
Rolling

Application Deadline

Jan 4, 2028

Date Added

Jan 5, 2023

This funding opportunity is designed to support a wide range of research proposals from universities, nonprofits, businesses, and government entities that aim to advance the U.S. Army's technological capabilities and operational effectiveness.

Science and Technology
Nonprofits
DoW Amyotrophic Lateral Sclerosis Research Program, Therapeutic Idea Award
$840,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 30, 2026

Date Added

May 5, 2026

This funding opportunity supports innovative research projects aimed at developing new therapies for amyotrophic lateral sclerosis (ALS), particularly those that include biomarker development to measure treatment effects, and is open to a wide range of researchers and organizations.

Health
Nonprofits
DoW Peer Reviewed Cancer, Clinical Trial Award
$4,500,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 5, 2026

Date Added

May 7, 2026

This funding opportunity supports clinical trials aimed at improving cancer treatment and management for various types of cancer, specifically targeting military populations and involving significant patient advocate participation.

Health
Nonprofits
A.12 Hemispheric Airborne Measurements of Air Quality (HAMAQ) Science Team
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Jul 21, 2026

Date Added

Apr 21, 2026

This funding opportunity supports U.S.-based institutions conducting airborne research to improve understanding of air quality and atmospheric pollutants on a hemispheric scale.

Science and Technology
Public and State controlled institutions of higher education
Research Program Award (R35 Clinical Trial Optional)
$750,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 15, 2026

Date Added

Sep 24, 2025

This funding opportunity provides substantial financial support for researchers in the neurosciences to pursue innovative, long-term projects while fostering mentorship and collaboration in the field.

Health
Nonprofits
Impact of Initial Influenza Exposure on Immunity in Infants (U01 Clinical Trial Not Allowed)
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 4, 2026

Date Added

Jul 9, 2025

This funding opportunity supports research to understand how infants' first encounters with influenza, through infection or vaccination, shape their long-term immune responses, with a focus on developing a universal flu vaccine.

Health
Public and State controlled institutions of higher education
Inspiring Generations Of New Innovators To Impact Technologies In Energy 2026 (IGNIITE 2026)
$500,000
U.S. Department of Energy (Advanced Research Projects Agency Energy )
Federal

Application Deadline

May 29, 2026

Date Added

Apr 24, 2026

This grant provides funding and mentorship to early-career scientists and engineers in the U.S. to develop innovative energy technologies that can significantly impact the energy sector.

Energy
Small businesses
Rfa-Dp-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides support for states, universities, and nonprofit organizations to enhance existing public health and injury prevention programs through administrative supplements to their current CDC grants.

Health
State governments
FY 2026 Ocean Technology Transition Program
$1,200,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Jul 15, 2026

Date Added

Mar 13, 2026

This funding opportunity provides financial support for universities, nonprofits, and government entities to develop and operationalize advanced ocean and coastal observing technologies that enhance data collection and environmental monitoring.

Environment
Public and State controlled institutions of higher education
F24AS00298 Cooperative Agriculture
Contact for amount
U.S. Department of the Interior (Fish and Wildlife Service)
Federal
Rolling

Application Deadline

Mar 7, 2029

Date Added

Mar 7, 2024

This grant enables individuals or entities to engage in agricultural practices on National Wildlife Refuge lands to support wildlife conservation and habitat management efforts without the exchange of federal funds.

Agriculture
Individuals
Environmental Security Technology Certification Program
$10,000,000
Environmental Security Technology Certification Program
Federal

Application Deadline

Aug 21, 2026

Date Added

Aug 26, 2025

This funding opportunity is designed for businesses, universities, and nonprofits to develop and demonstrate innovative technologies that improve environmental and energy efficiency for the U.S. Department of Defense.

Science and Technology
Small businesses
Defense Production Act Title III Expansion of Domestic Production Capability and Capacity
$25,000,000
U.S. Department of Defense (Air Force -- Research Lab)
Federal

Application Deadline

Jul 12, 2026

Date Added

Jul 12, 2019

This funding opportunity provides financial support to U.S. companies and organizations to boost domestic production capabilities for critical defense materials and technologies, ensuring national security and resilience in the industrial base.

Science and Technology
For profit organizations other than small businesses
Engineering Environmental Resiliency (EER)
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 27, 2026

This program provides funding for U.S.-based researchers and institutions to develop innovative technologies and processes that enhance environmental sustainability and resilience while promoting efficient resource use.

Science and Technology
Public and State controlled institutions of higher education