Federal Health Grants

This project seeks to further refine and geographically expand a methodology for obtaining drug early warning indicators through broader testing of urine samples that were previously collected and tested as part of an existing drug test protocol. This method was initially developed using local criminal justice populations including persons in pre-trial or lock-up, parolees or probationers, and drug court participants. A similar methodology is promising for use in other venues, such as in trauma units and emergency departments, where biological samples are often collected from patients. Before the specimens are discarded, the project will re-test them for an expanded panel of drugs, including xylazine, fentanyl, methamphetamine, and other new psychoactive substances (NPS); to determine what old and new illicit drugs are detected or missed by conventional testing protocols, and how the drug patterns might vary by subpopulation and geography. Bypassing the expense of collecting the original specimens and re-using those that have already been tested with known results yields a relatively inexpensive and timely picture of emerging drugs in a given subpopulation and locality. Hospital and de-identified nationally representative patient electronic health records (EHRs) should be collected and analyzed to put re-tested urine positivity results into a larger regional and national context of drug exposure and consequences. ONDCP is seeking to apply this testing methodology and insight from supplemental EHR investigations to emergency department and other hospital-system populations in locations throughout the United States to reinforce best practice guidelines, testing standardization, and build local and national surveillance capacity.

This funding opportunity supports early-stage research to develop new therapeutic agents for heart, lung, blood, and sleep disorders, specifically targeting projects that have identified promising small molecules or biologics ready for preclinical testing.

The Metastasis Research Network (MetNet) Research Projects grant aims to fund research projects that use comprehensive, systems-level approaches to address gaps in metastasis research, particularly focusing on themes like dormancy, early dissemination, and cellular or physical microenvironment interactions, with the goal of enhancing our understanding of metastasis as a whole-body, systems-level issue.

This program provides funding to communities across the U.S. to implement strategies that prevent and reduce alcohol use among youth and young adults aged 12 to 20.

This funding opportunity supports the establishment of research centers that leverage artificial intelligence and technology to advance studies in aging and Alzheimer's disease, inviting interdisciplinary teams from various organizations to innovate and train in this critical field.

The purpose of the NOFO is to establish and maintain a network of Regional Centers for Public Health Preparedness and Response to increase implementation of evidence-based strategies and interventions (EBSIs) and to improve public health preparedness and response, as informed by the needs of the communities involved. Support will be provided for up to ten centers to determine and support implementation of activities needed to increase use of EBSIs that will improve public health preparedness and response, as informed by the needs of the communities as described in regional workplans. The goal is to fund one center in each of the 10 HHS Regions. Each center will1) Coordinate relevant activities with applicable State, local, and Tribal health departments and officials, health care facilities, and health care coalitions to improve public health preparedness and response, as informed by the needs of the community, or communities involved.2) Develop and implement activities to support focus areas and objectives created by a regional coordinating body in 2023-24.3) As determined necessary by the CDC, and based on the availability of funding, support further implementation of evidence-based practices, or conduct research, evaluation, translation or dissemination necessary to address active or anticipated public health emergencies.4) One center will be awarded additional funds to support coordination and convening of centers and provide technical assistance and training as needed.

This funding opportunity supports innovative research projects that explore the intersection of HIV and substance use disorders, aiming to develop transformative strategies for prevention, treatment, and potential cures in affected populations.

This funding opportunity supports researchers developing innovative computational tools and methods to advance genomics, particularly those new to the field or from underrepresented groups.

This Notice of Funding Opportunity (NOFO) announces the opportunity to apply for funding under the Health Center Programs Service Area Competition (SAC). The purpose of this funding is to ensure continuity of care in the communities and populations currently served by the Health Center Program. See Program Requirements and Expectations for more details.

This funding opportunity provides financial support to institutions in low- and middle-income countries to enhance their capacity for managing research grants from the National Institute of Allergy and Infectious Diseases through advanced training and strategic development.

This program provides access to valuable health data for researchers focused on improving health outcomes and reducing disparities among underserved populations in the U.S.

The National Institutes of Health (NIH) Office of Data Science Strategy (ODSS), with other NIH Institutes and Centers (ICs), intends to promote aninitiative by publishing a Funding Opportunity Announcement (FOA) to solicit applications for early-stage biomedical data repositories or knowledgebases.This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NIH intends to continue the Database and Knowledgebase program beyond the January 25, 2023, receipt date of the current FOAs (PAR-23-078 andPAR-23-079) . This new FOA will support early-stage biomedical data repositories and knowledgebases. This Notice of Intent to Publish (NOITP) is being provided to allow potential applicants time to develop meaningful community engagement, collaborations, and NIH consultations to submit applications for responsive data repositories and knowledgebases as trans-NIH data resources. The FOA is expected to be published in Spring 2023 with an expected application due date in Fall, 2023. This FOA will utilize the R24 activity code. Details of the planned FOAs are provided below.

The "Notice of Intent to Publish a Notice of Funding Opportunity for Centers on the Demography and Economics of Aging, Including Alzheimer's Disease and Alzheimer's Disease-Related Dementias (AD/ADRD) (D Centers) (P30 Clinical Trial Optional)" grant aims to fund the development or renewal of research centers focused on advancing aging research in demography, economics, and related social sciences, with a particular emphasis on Alzheimer's disease and related dementias, while promoting innovative research, addressing health disparities, and fostering interdisciplinary collaboration.

The "Epidemiologic Research on Emerging Risk Factors and Liver Cancer Susceptibility" grant is a funding opportunity by the National Cancer Institute for research projects that aim to investigate new and existing risk factors of liver cancer, including biological, environmental, and social factors, to enhance understanding of the disease and inform prevention strategies in the U.S.

This funding opportunity supports research projects aimed at developing new medications for treating various substance use disorders, encouraging innovative approaches and collaboration between researchers and behavioral therapy integration.

Subject: Jordan RFI/SSN: Prevent, Detect, Respond - Primary Health Care (PDR-PHC) ActivityThe United States Agency for International Development in Jordan (USAID/Jordan) Mission isgathering information for a potential Global Health Security (GHS) activity. The Activity willinclude a package of interventions to strengthen biosecurity and safety, address antimicrobialresistance (AMR), and prevent and respond to emerging threats through building One Healthcapacities that incorporate linkages between human, animal, and environmental health.Through focusing its interventions at the primary healthcare level, the activity will strengthenhealth provider practices, health system preparedness, multi-sectoral coordination, andsurveillance capabilities to 1) prevent avoidable disease outbreaks, 2) detect threats early, 3)respond rapidly and effectively when outbreaks occur.This RFI/SSN seeks responses to the below inquiries as well as information on the availability,interest, and diverse capacities of GHS-focused entities to carry out such tasks and theirability to collaborate with local entities.This RFI/SSN is issued solely for information and planning purposes. It is NOT a Request forProposal (RFP), nor Notice of Funding Opportunity (NOFO), and in no way obligates the U.S.Government to issue an RFP/NOFO and/or award a contract/grant or pay for any informationsubmitted as a result of this request. If a solicitation is issued, all necessary information willbe supplied at the time it is posted at grants.gov or sam.gov.

The FY 2024 Strategic Prevention Framework-Partnerships for Success (SPF-PFS) funding opportunity from the Substance Abuse and Mental Health Services Administration (SAMHSA) targets substance misuse prevention and mental health promotion across communities, universities, colleges, local governments, and tribal organizations. This program aims to enhance local and tribal prevention capacity, particularly within underserved communities. SAMHSA will fund projects that use data-driven, community-centered strategies aligned with the Strategic Prevention Framework (SPF), a model designed to assess, plan, and implement evidence-based prevention programs that address substance misuse risks in youth and adults. Eligible applicants include public and private nonprofit entities, such as local governments, universities, tribal organizations, and community-based organizations. Grants are awarded for up to five years, with a maximum of $375,000 per year. The total available funding is estimated at $15.5 million for FY 2024. Applications are due by February 21, 2024, with projects expected to begin by September 30, 2024. Notably, organizations already funded under similar SAMHSA grants in recent years are ineligible to apply to avoid overlap with existing initiatives. The grant prioritizes activities that promote culturally competent and sustainable prevention services. Required activities include conducting needs assessments, engaging local stakeholders, developing prevention strategies, and implementing monitoring and evaluation measures. Projects should aim to reduce substance use issues, including underage drinking, opioid misuse, and tobacco use. SAMHSA encourages coordination with local and state agencies, specifically through SPF-PFS State awardees when applicable. Applications must include a project narrative (10-page maximum), budget justifications, letters of commitment from partners, and a data collection plan. Key personnel, such as a Project Director and Data Analyst, are required to devote at least 0.5 FTE each to the project. Successful applicants will also create a Disparity Impact Statement to outline plans for addressing behavioral health disparities in their target communities. Evaluation of applications will consider factors such as community need, clarity of the project plan, organizational experience, and cost-effectiveness. Applications that prioritize underserved communities are eligible for bonus points. Awardees must submit quarterly and annual performance reports detailing project outcomes, including data on individuals reached and changes in local substance misuse patterns.

This funding opportunity provides financial support to projects that improve health information resources for underserved populations, helping to reduce health disparities and promote better health outcomes through collaboration with medical libraries.

The "Notice of Intent to Publish a Notice of Funding Opportunity for Centers on the Demography and Economics of Aging and Alzheimer's Disease and Alzheimer's Disease Related Dementias Coordinating Center" grant is intended to fund the development or renewal of a coordinating center that will serve as a hub for various research centers, enhancing their scientific impact, fostering synergies, promoting inclusivity, and raising the profile of aging and Alzheimer's disease research.

This funding opportunity supports innovative research projects that aim to improve health outcomes through the equitable use of genomics, particularly for underrepresented populations in the U.S.