Federal Science and Technology Grants

The FY24 KCRP Concept Award supports highly innovative, untested, potentially groundbreaking novel concepts in kidney cancer. The Concept Award is not intended to support an incremental progression of an already established research project but, instead, it allows Principal Investigators (PIs) the opportunity to pursue serendipitous observations. Preliminary data are not allowed and should not be discussed. This award mechanism supports high-risk studies that have the potential to reveal entirely new avenues for investigation. Applications must describe how the new idea will enhance the existing knowledge of kidney cancer or develop an innovative and novel course of investigation. Research completed through a Concept Award may generate sufficient preliminary data to enable the PI to prepare an application for future research.Organizational-Level Emphasis Areas:The following areas of emphasis are broadly applicable to many CDMRP programs, not just the KCRP. Investigators are encouraged to consider addressing these areas in their applications if doing so is appropriate for their line of research, addresses the FY24 KCRP strategic priorities and/or focus areas described in Section II.A.1 and Section II.A.2.Nuclear Medicine: Innovative research involving nuclear medicine and related techniques to support early diagnosis, more effective treatment, and improved health outcomes of active-duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies.Womens Health: CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in womens health outcomes and/or advancing knowledge for womens health.Metastatic Cancer Task Force: A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 KCRP priorities.Rigorous Study Design: All projects should adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of clinical and preclinical research. The standards are described in SC Landis et al., 2012, A call for transparent reporting to optimize the predictive value of preclinical research, Nature 490:187-191 (https://www.nature.com/nature/journal/v490/n7419/full/nature11556.html). While these standards are written for preclinical studies, the basic principles of randomization, blinding, sample-size estimation, and data handling derive from well-established best practices in clinical studies.Military Service Involvement: Applications from investigators within the military services and applications involving multidisciplinary collaborations among academia, industry, the military services, the U.S. Department of Veterans Affairs (VA), and other federal government agencies are highly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the collaborators bring to the research effort, ultimately advancing research that is of significance to Service Members, Veterans, and/or their Families. If the proposed research relies on access to unique resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research.Reviewers will be blinded to the identity of the Principal Investigator (PI), collaborator(s), and their organization(s). Refer to Section II.D.2.b.i, Full Application Guidelines, for more information.Clinical trials are not allowed under this funding opportunity.A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).The anticipated direct costs budgeted for the entire period of performance for an FY24 KCRP Concept Award should not exceed $100,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $1.44M to fund approximately nine Concept Award applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

This funding opportunity supports U.S. institutions conducting theoretical astrophysics research to improve our understanding of cosmic phenomena through innovative modeling and data interpretation.

This grant provides funding for interdisciplinary teams of graduate students, researchers, and industry professionals to explore and propose solutions for integrating renewable energy into the U.S. electric grid.

This funding opportunity supports collaborative research and mentorship projects in science, particularly aimed at enhancing participation and career development for underrepresented groups in STEM fields across diverse academic institutions.

This funding opportunity provides financial support for local non-government organizations in Algeria to implement projects that foster cultural, educational, and scientific exchanges between the United States and Algeria.

This grant provides funding for researchers focused on understanding solar activity and its effects on the Earth's environment, aiming to improve predictions of space weather events.

This grant provides funding for research in physical sciences, targeting a wide range of organizations, including government and private entities, to advance knowledge and technology in space and Earth sciences.

Collaboration Opportunity Announcement (COA) for Parties Interested in Partnering with the National Energy Technology Laboratory (NETL) under FOA 24-3210 Competitive Portfolios for Advanced Scientific Computing Research This is only an opportunity notice. Any information contained in this opportunity notice is subject to change. DOE will not respond to individual submissions or publish a compendium of the responses made to this opportunity notice. A submittal in response to this opportunity notice shall not constitute or create a binding commitment to develop or pursue the project or ideas discussed within a particular submittal. DOE is under no obligation to partner or collaborate with any entity who submits a response to this opportunity notice. DOE may choose to partner or collaborate with one or more or none of the responding entities. The terms and conditions of any resulting partnership or collaboration shall be memorialized in a future written agreement. The costs incurred to submit a response to this opportunity notice will not be borne by the Government.

This funding opportunity provides financial support for researchers to explore the molecular mechanisms that enhance the productivity and resilience of bioenergy crops, while also investigating the role of microbial communities in promoting plant health and sustainability.

The Military Health System Research Program (MHSRP) provides research grants on topic areas directed by the Office of the Assistant Secretary of Defense for Health Affairs (OASD (HA)) and the Leadership of the Defense Health Agency (DHA). The intent of MHSR is to foster research capability and capacity that supports the Military Health System (MHS) as a learning health system and to mature as an integrated health system focused on Ready Reliable Care that improves outcomes for patients, staff, and the enterprise. The MHSRP funds research that examines factors that affect the enterprise in terms of economics/cost, quality, outcomes, variation, policies, and how they impact health readiness. The goal is to identify and characterize the factors that influence the efficiency and effectiveness of MHS care delivery. Knowledge obtained from this research should support evidence-based policy and decision-making at the strategic and front-line levels. This Notice of Funding Opportunity (NOFO) seeks rigorous collaborative health system research that has the potential to innovate military and civilian health care. The goal is to enhance data-driven evidence that optimizes the MHS delivery of health care and improves the health of beneficiaries. This NOFO is intended to solicit Intramural and Extramural Military Health System Research aligned with DHA priority research areas.

This funding opportunity invites interdisciplinary teams from U.S. institutions to collaborate on advanced computing projects that enhance scientific discovery in energy-related fields using high-performance computing resources.

The "Ideas Lab: Breaking the Low Latency Barrier for Verticals in Next-G Wireless Networks" grant aims to fund research and development initiatives that seek to overcome technical challenges in 5G and next-generation wireless networks, with the goal of achieving consistently low-latency performance necessary for the success of emerging industries, through collaborative brainstorming, prototyping, and testing of innovative solutions.

FY2025 Weather Program Office Research Programs Announcement - Testbeds aims to fund projects that advance applied weather research and improve forecasting tools for severe weather hazards by collaborating with NOAA's testbeds to ensure practical application in real-world forecasting operations.

This grant provides funding for researchers and organizations to conduct studies and develop technologies related to the workings of the solar system, supporting a wide range of scientific investigations in planetary science.

1) Note: A full study proposal and proposed budget are NOT requested at this time.2) Project Title: Cultural Resources Support for Dugway Proving Ground in Utah.3) Brief Description of Anticipated Work: The recipient/cooperator agrees to provide the necessary personnel, equipment, and materials required to conduct comprehensive cultural resources support, within the Dugway Proving Ground, Division of Environmental Programs, Cultural Resources Program, located at Dugway Proving Ground, Tooele County, Utah. The scope of this agreement includes supporting the program manager (PM) through the implementation of Dugways Integrated Cultural Resources Management Plan (ICRMP) and all aspects of the Dugway Cultural Resource program focusing on supporting the National Historic Preservation Act (NHPA), National Environmental Policy Act (NEPA), Archaeological Resources Protection Act (ARPA), American Indian Religious Freedom Act (AIRFA), and Executive Order EO 13007; Native American Graves Protection and Repatriation Act (NAGPRA); 36 CFR 79; DoDi 4710.02 DoD Interactions with Federally Recognized Tribes; and AR 200-1.4) Period of Performance: The base period of performance (PoP) will be 12 months from date of award. Up to six (6) Follow-On Periods with 12-month period of performance foreach.5) Please send responses or direct questions to:Nicholas ApreaGrants SpecialistUSACE, Fort Worth DistrictEmail: Nicholas.A.Aprea@usace.army.milBrian HesfordProject ManagerUSACE, Fort Worth DistrictEmail: brian.d.hesford@usace.army.mil6) Timeline for Review of Statements of Interest: 30 calendar days from date posted.

The SCIRP TRA is intended to support translational research that will accelerate the movement of promising ideas in SCI research into clinical applications. Although not all-inclusive, some examples include demonstration studies of pharmaceuticals and medical devices in preclinical systems and/or clinical research on therapeutics, devices, or practice using human tissues or resources.The ultimate goal of translational research is to move an observation forward into clinical application and accelerate the clinical introduction of health care products, technologies, or practice guidelines. Observations that drive a research idea may be derived from a laboratory discovery, population-based studies, or a clinicians first-hand knowledge of patients and anecdotal data. However, applicants should not view translational research as a one-way continuum from bench to bedside. The research plan is encouraged to involve a reciprocal flow of ideas and information between basic and clinical science.

This initiative provides funding to defense contractors and formal methods developers to enhance cybersecurity in military software systems by integrating advanced verification tools.

This funding opportunity provides financial support for pilot projects that recover critical minerals and materials from industrial processes in the U.S., targeting both coal-based and other industries to enhance domestic supply chain security.

This funding opportunity provides financial support for research and development in accelerator technology, targeting academic institutions, national labs, and for-profit companies to advance innovations that benefit multiple scientific fields and enhance domestic manufacturing capabilities.

The American-Made Electronics Scrap Recycling Advancement Prize (E-SCRAP) is a $3.95 million challenge sponsored by the U.S. Department of Energy’s (DOE) Advanced Materials and Manufacturing Technologies Office (AMMTO). This three-phase prize aims to stimulate innovative approaches that reduce the costs and environmental impact of critical material recovery from electronic scrap (e-scrap). The program aligns with the DOE's mission to advance energy technology and reduce environmental impact, specifically targeting the challenges within the e-scrap recycling value chain. The target beneficiaries of the E-SCRAP prize are individuals, private entities (for-profits and nonprofits), nonfederal government entities (states, counties, tribes, and municipalities), and academic institutions working in waste collection and management, dismantling and sorting, separation, refining, validation, and material supply. The impact goals are to increase the domestic supply of critical materials from e-scrap, enhance material circularity, and reduce the environmental footprint associated with current recycling processes. The program prioritizes innovative approaches, processes, or technologies that optimize and implement critical material separation and recovery from e-scrap. This includes building partnerships across the recycling value chain, developing and demonstrating innovations, addressing technical, supply chain, or logistical hurdles, and enhancing supply chains to accelerate connectivity between various stages of recycling. Areas of interest include innovations for electronic scrap (communication devices, home appliances, medical/office equipment) and the recovery of critical materials such as aluminum, cobalt, copper, lithium, nickel, and rare earth elements. Expected outcomes include the development and demonstration of new technologies that lead to more efficient and environmentally friendly e-scrap recycling processes. Measurable results will be seen in increased rates of critical material recovery, reduced costs, and a decrease in environmental impact. Competitor teams can win up to $800,000 in cash prizes and $150,000 in national laboratory analysis support. The prize’s strategic priorities are to act as a catalyst for change, fostering innovation and collaboration to strengthen the domestic supply chain of critical materials, thereby contributing to clean energy initiatives and a more circular economy.