Grants for For Profit Organizations Other Than Small Businesses

The goals of the paleoclimate program are to: (i) provide a baseline for present climate variability and future climate trends, and (ii) improve the understanding of the physical, chemical, and biological processes that influence climate variability and trends over the long-term. Research topics include observational and modeling studies of past climate variability and its drivers and studies that develop new paleoclimate proxies and records. Competitive proposals will address specific aspects of scientific uncertainty for their proposed research. The Paleoclimate program of the Division of the Atmospheric and Geospace Sciences together with other Divisions in the Geoscience Directorate have joined in coordinating and supporting the annual Paleo Perspectives on Present and Projected Climate (P4CLIMATE) competition with the objectives to support studies within two research themes: 1) Past Regional and Seasonal Climate; and 2) Past Climate Forcing, Sensitivity, and Feedbacks. Researchers are encouraged to consider the P4CLIMATE competition as a possible source of support for their global change research. Since proposals eligible for funding in the P4CLIMATE competition are not eligible for funding in the Paleoclimate Program, researchers are strongly advised to contact the Directors of the Paleoclimate Program for guidance as to the suitability of their proposed research for either program. The paleoclimate program strongly encourages proposals from: Researchers at all career stages, including through the AGS Postdoctoral Research Fellowship program. Researchers at all institution types, including MSIs, non-R1 institutions, and institutions in EPSCoR jurisdictions. Researchers from traditionally underrepresented groups in Paleoclimate Science.

The Program supports research on the sources, sinks, transport, and transformation of gases and aerosols in the atmosphere through models, observations, and experiments, including homogeneous and heterogeneous chemical reactions, emissions, deposition, atmospheric oxidation and photochemistry, aqueous-phase chemistry and aerosol processes; the formation of new particles and secondary organic aerosols, the modeling of atmospheric chemical processes, the study of chemical mechanisms in the atmosphere, optical properties of gases and aerosols, and improved methods for measuring the concentrations of trace species and their fluxes into and out of the atmosphere.The Program encourages principal investigators from a wide variety of institutions and backgrounds to submit proposals.

This funding opportunity supports innovative medical research projects that enhance the health and readiness of U.S. service members and benefit civilian populations, inviting submissions from a wide range of qualified applicants.

This funding opportunity supports researchers and institutions in developing innovative technologies and instruments to enhance ground-based astronomical observations and advance the field of astronomy in the U.S.

Pursuant to the Foreign Assistance Act of 1961, as amended, the United States Government, as represented by the U.S. Agency for International Development (USAID), the Bureau for Development, Democracy, and Innovation (DDI), Inclusive Development Hub (ID) is announcing the Alliance to Advance Protection and Care for Children in Adversity (APCCA) Annual Program Statement (APS). Through the APCCA Alliance APS, USAID aims to address key objectives outlined in the U.S. Government (USG) Advancing Protection and Care for Children in Adversity Strategy. The purpose of this APS is to disseminate information to prospective Applicants so they may develop and submit Concepts in response to future Addenda under this APS and ultimately to be considered for USAID funding. USAID DDI/ID anticipates awarding multiple grants and/or cooperative agreements as a result of this APS. However, issuance of this APS does not constitute an award commitment on the part of the U.S. Government, nor does it commit the USG to pay for any costs incurred in the preparation or submission of comments/suggestions, a concept, or an application. Concepts and Applications are submitted at the risk of the applicant. All preparation and submission costs are at the applicants expense. The actual number of assistance awards, if any, under this APS is subject to the availability of funds and the interests and requirements of Operating Units (OUs) as well as the viability of eventual Full Applications received. There is no predefined minimum or maximum number of awards USAID OUs will support through this APS. The APCCA APS is unfunded and serves as a general umbrella APS, to which any USAID OU can post specific Addenda that are focused on challenges or priorities highlighted in the APS. An Addendum highlights a specific program or activity, where technical assistance or partnership opportunities are communicated by a USAID OU. Addenda will be the exclusive source of funding through this APS. NOTE: This APS is not a Request for Applications or a Request for Proposals, and does not serve as a general request for APCCA concepts. USAID will only consider Concepts that are submitted in response to Addenda to this APS. USAID will not accept or consider any Concepts submitted in response to the general APCCA Alliance APS. Addenda will be posted on www.grants.gov. Based on the submitted Concept(s) to specific Addenda opportunities, USAID will determine whether to engage in more in-depth and specific co-creation discussions aimed at further developing the proposed approach and will determine whether to request a Full Application. To be competitive under a particular Addendum to this umbrella APS, Concepts and Full Applications must be fully responsive to all directions under this APS document except when specifically noted otherwise in the Addendum. Please refer to the full APS document attached for full information and details about this opportunity.

Microbes and communities of microbes have remarkable genetic, physiological and biochemical diversity, allowing them to flourish in environments all over the planet and in a variety of substrates and hosts. Given their relative importance to ecosystems around the world, to the economy and to health, researchers have studied microbial systems extensively and have a better understanding of their capabilities and impacts on hosts and the environment. In recent years, researchers have increasingly turned to microbes and their diverse capabilities for bioremediation and applications in biotechnology, agriculture, and medicine. Because of advances in molecular biology, synthetic biology and bioengineering, researchers now have the ability to assemble synthetic microbial communities that have novel compositions, genetics and phenotypes and to use these communities to address both fundamental biological questions and a range of societal problems. The goal of this solicitation is to support research that addresses one or more of the three themes: 1) define the underlying mechanisms or rules that drive the formation, maintenance or evolution of synthetic microbial communities, 2) use synthetic microbial communities to address fundamental biological questions, including questions in molecular biology, cellular/organismal biology, ecology and evolution and/or 3) build synthetic communities with biotechnology, bioeconomy or environmental engineering applications, including but not limited to the production of novel biorenewable chemicals, biodegradation of recalcitrant or forever chemicals, enabling a circular bioeconomy, fostering sustainable agriculture and mitigating the impacts of climate change. For theme 3, the emphasis should be on designing communities with novel capabilities and understanding the underlying mechanisms that lead to these novel capabilities. Proposals must address one or more of the three themes noted above. Highest funding priority is given to proposals that have outstanding intellectual merit and broader impacts, while proposals with weaknesses in either category (or those that are perceived as likely to have an incremental impact) will not be competitive. The most competitive broader impacts include assessment plans. Well-conceived broader impacts activities take time and resources; thus, proposers are encouraged to include appropriate costs for broader impacts in the budget. To better understand the societal benefits and risks, as well as the potential for misuse or unintended damage to natural biological systems, synthetic microbial communities proposals should include a careful consideration of the social, ethical, and biosafety/security dimensions of the research. Investigators may choose to address these issues either as part of intellectual merit or broader impacts. Reproducibility in research leads to data that is amenable to more powerful analysis and the potential for reuse of data and greater generation of knowledge. Reproducibility in biological research that is prone to context dependent biological variation presents a unique challenge for the synthetic microbial communities researchers. Investigators must follow or advance best practices in sample collection and preparation, experimental design, data analysis, model generation, and/or validation of mathematical and computational methods to produce scientifically defensible results.

This grant provides funding for researchers studying ancient sediments and fossils to better understand the Earth's history, environmental changes, and the evolution of life before the Holocene epoch.

This funding opportunity provides financial support to organizations that empower young leaders in Southeast Asia to tackle climate change and environmental challenges through leadership training, collaboration, and capacity-building initiatives.

The National Institute on Aging is offering a grant for graduate students interested in aging-related research, providing funding and support for their doctoral dissertation projects and transition into postdoctoral positions in the field.

Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) invites U01 cooperative agreement applications for Physical Sciences-Oncology Network (PS-ON). The goal of the PS-ON is to foster the convergence of physical sciences approaches and perspectives with cancer research to advance our understanding of cancer biology and oncology by forming transdisciplinary teams of physical scientists and cancer biologists/physician scientists. Examples of physical scientists may include engineers, physicists, mathematicians, chemists, and computer scientists. The research projects funded through this FOA, individually and as a collaborative Network along with other funded research projects, will support transdisciplinary research that: (1) drives a physical sciences perspective within the cancer research community; (2) facilitates team science and field convergence at the intersection of physical sciences and cancer research; and (3) collectively tests physical sciences-based experimental and theoretical concepts of cancer and promotes innovative solutions to address outstanding questions in cancer research.

This funding opportunity provides additional financial support to active health services research projects facing unforeseen costs, helping researchers continue their work effectively.

This funding opportunity supports researchers in engineering and related fields to explore and improve the behavior, diagnostics, and control of dynamic systems through innovative theoretical, computational, or experimental studies.

This funding opportunity supports innovative research in air-delivered munitions, targeting educational institutions, non-profits, and private companies, particularly small businesses, to advance technologies in weapon systems, sensors, and related fields for the Air Force.

The STRIPE program grant is designed to fund pre-clinical research that explores how radiopharmaceutical therapy affects cancer cells and their environment, with the aim of developing new targeting strategies and informing the design of future RPT-based clinical trials.

This grant provides funding to exceptional U.S.-based graduate students transitioning from predoctoral to postdoctoral research in kidney, urologic, or hematologic sciences, encouraging diverse talent to contribute to these fields.

The NSF Engineering (ENG) Directorate has launched a multi-year initiative, theProfessional Formation of Engineers, to create and support an innovative and inclusive engineering profession for the 21stcentury. Professional Formation of Engineers (PFE) refers to the formal and informal processes and value systems by which people become engineers. It also includes the ethical responsibility of practicing engineers to sustain and grow the profession in order to improve quality of life for all peoples. The engineering profession must be responsive to national priorities, grand challenges, and dynamic workforce needs; it must be equally open and accessible to all. Professional Formation of Engineers includes, but is not limited, to: Introductions to the profession at any age; Development of deep technical and professional skills, knowledge, and abilities in both formal and informal settings/domains; Development of outlooks, perspectives, ways of thinking, knowing, and doing; Development of identity as an engineer and its intersection with other identities; and Acculturation to the profession, its standards, and norms. The goal of the Research in the Formation of Engineers (RFE) program is to advance our understanding of professional formation. It seeks both to deepen our fundamental understanding of the underlying processes and mechanisms that support professional formation and to demonstrate how professional formation is or can be accomplished. Ultimately RFE aims to transform the engineer-formation system, and thus the impact of proposed projects on this system must be described. Principal Investigators (PIs) should provide a roadmap detailing how they envision the proposed research will eventually broadly impact practice within the engineer-formation system, even if these activities are not within the scope of the submitted proposal. In order to accomplish its goals, RFE welcomes proposals in two categories: Research Projects, and Design and Development Projects. Research Projects address fundamental questions of professional formation, while Design and Development Projects provide new approaches to achieving professional formation. Additional details are provided below. Projects in both categories should address the iterative cycle in which research questions that advance understanding are informed by practice and the results of research are, in turn, translated into practice. In other words, proposals should explain how the research results will travel, translate, transfer, or scale. Successful projects identify specific target audiences, effective communication channels, and novel partnerships to ensure effective propagation and scaling. Proposal titles should begin with either Research: or Design and Development: as appropriate. Research Projects Research proposals are particularly welcome in the following areas: Research that addresses lifelong learning by the engineering workforce. Research on the impact of engineering education research. Proposals addressing this topic could investigate questions such as: How can we measure the impacts of engineering education research? What are effective strategies for scaling reforms? How can we translate knowledge from research to practice? What are the roles of technologies, networks and communities in achieving impact? RFE does not support efficacy, effectiveness, or scale-up studies for specific interventions. Research that addresses culture change in engineering education. Included in this topic are investigations of normative cultures of engineering at any level in the engineering education ecosystem and how these cultures may disadvantage certain groups. Research that addresses engineering formation at the two-year college and graduate education levels in both formal and informal settings. Research that investigates engineering in P?12 settings. Research in this area could include understanding of approaches to engineering in P?12, how to develop engineering ways of thinking, or the relationship between practices within the sciences and mathematics and engineering thinking. Research on the transitions between education levels, e.g., from high school to two-year college, high school to four-year college/university, two-year college to four-year college/university, undergraduate to graduate school, education settings to the workforce or professoriate, etc. Research that addresses the relationship between engineering and the public. Proposals addressing this topic could consider the social impact of engineering solutions, citizen engineering, education of an informed public, etc. Research that develops or adapts novel methodologies and frameworks appropriate for studying the professional formation of engineers, and especially minoritized, marginalized, or underserved populations. Research that addresses ways in which new technologies (such as artificial intelligence and machine learning) are changing engineering education. Proposals submitted to the Research Projects category should have clear research questions informed by an appropriate theoretical framework and a research design that includes sampling, data collection, and data analysis methods. This category will not support proposals that seek funding primarily to develop tools, curriculum, or laboratories, or that seek to implement classroom innovations that have already been shown to be effective in engineering. The program will evaluate the value of proposals by considering the impact and the cost. Research track projects that are small, exploratory, or speculative are especially encouraged. Larger Research track projects should have a correspondingly larger impact. Design and Development Projects RFE supports Design and Development projects (see https://www.nsf.gov/publications/pub_summ.jsp?ods_key=nsf13126) that seek to develop and test new approaches in the following areas: Graduate education. Transitions between education levels, e.g. high school to two year college, high school to 4 year college/university, two year college to 4 year college/university, undergraduate to graduate school, education settings to the workforce or professoriate, etc. K12, especially approaches to develop engineering thinking, or providing links between engineering, science, and mathematics Proposals in this category should propose the design and development of new approaches that are informed by existing literature and theory. There should be clear objectives and the evaluation plan should be designed to determine if those objectives have been met. Projects cannot be solely demonstration projects, but must add to the engineering education literature to inform future work.

This grant provides funding for researchers in atmospheric sciences to access advanced facilities and instruments necessary for studying various geophysical phenomena.

**AMENDED on DECEMBER 11 2023**: The latest revision is posted as Amendment 18. Potential applicants are strongly encouraged to review the Amendment in its entirety, as it updates several sections. Specifically, ATTACHMENT 1: SPECIFIC TOPICS now includes Basic Research Topics N1-N4, with white papers due by 11:59pm EST on 5 February 2024. White papers may not be considered if they are received after this deadline. In addition, submissions to the general thrust areas in accordance with the requirements detailed in the BAA are also welcome. ** Please note that all correspondence must be sent to the appropriate Agency contact identified in Section 7. Agency Contacts. **

This funding opportunity supports researchers in the U.S. working to improve models of the Earth's geospace environment, focusing on the interactions between the magnetosphere, atmosphere, and solar wind, while encouraging innovative approaches like machine learning and collaboration among diverse teams.

This grant provides funding to organizations working to improve health outcomes in family planning, maternal and child health, and HIV/AIDS by promoting effective policies and sustainable financing in developing countries.